Polygonatum odoratum
Polygonatum odoratum
Polygonatum odoratum, commonly known as Solomon's seal, is a traditional medicine used in East Asian practices. While its specific uses are not well-documented historically, modern research suggests potential benefits for various conditions. Studies indicate that Polygonatum odoratum may have anti-pruritic effects and could influence glucose and lipid metabolism, suggesting possible applications in managing type 2 diabetes. Additionally, some compounds from the plant showed varying levels of cytotoxicity against certain cancer cell lines, though more research is needed to confirm these findings. Safety-wise, no major issues have been recorded, and there are currently no known drug interactions associated with Polygonatum odoratum.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- This study identified multiple targets suggesting Polygonatum odoratum may have anti-pruritic effects through various pathways.
- The polysaccharide content in Polygonatum odoratum rhizomes peaked in spring, with key regulatory enzymes and a transcription factor identified.
- Polygonatum odoratum protein hydrolysate improved glucose and lipid metabolism, reduced tissue damage, and enhanced antioxidant defense in type 2 diabetic mice.
- Four new compounds from Polygonatum odoratum showed varying levels of cytotoxicity against certain cancer cell lines, with some inhibiting thymidylate synthase.
Frequently asked questions
What is Polygonatum odoratum?
Polygonatum odoratum (Polygonatum odoratum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Polygonatum odoratum?
4 sourced findings are recorded for Polygonatum odoratum; the strongest carries evidence grade D. For example: This study identified multiple targets suggesting Polygonatum odoratum may have anti-pruritic effects through various pathways.
How strong is the evidence for Polygonatum odoratum?
The strongest finding for Polygonatum odoratum carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Polygonatum odoratum safe? What are the side effects?
No major safety issues are recorded for Polygonatum odoratum in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Polygonatum odoratum interact with medications?
No drug interactions are recorded for Polygonatum odoratum in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Polygonatum odoratum?
Polygonatum odoratum is also known as: Купена аптечная, Sceau de Salomon odorant.
Is Polygonatum odoratum a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Unlocking the potential of Polygonatum odoratum protein hydrolysate: identification, characterization, and antidiabetic activity in HFD/STZ-induced type 2 diabetic mice. literature abstract metadata
- T2 Integration of metabolomics and proteomics reveals the mechanisms of seasonal accumulation and key regulatory networks of polysaccharides in Polygonatum odoratum. literature abstract metadata
- T2 Elucidating the Multi-Target Anti-Pruritic Mechanism of Polygonatum odoratum via Integrated Network Pharmacology, Molecular Simulations, and GEO Dataset Validation. literature abstract metadata
- T2 Four undescribed sappanin-type homoisoflavanones isolated from Polygonatum odoratum with anti-tumor effects and molecular docking study. literature abstract metadata