Catfoot
Pseudognaphalium obtusifolium
Pseudognaphalium obtusifolium is a plant traditionally used in various folk medicine practices, particularly in Europe and Asia. However, there are no specific traditional uses documented for this particular species. Scientific evidence regarding its medicinal properties is limited; studies focusing on related plants have shown mixed results. For instance, methanol extracts from Ruta chalepensis demonstrated selective cytotoxic activity against certain cancer cells but showed low hemolytic activity and minimal toxicity in cell cultures. Similarly, Justicia spicigera's methanol extract exhibited significant lymphoma cell growth inhibition with a favorable selectivity index. However, these findings are not directly applicable to Pseudognaphalium obtusifolium due to the lack of specific research on this species. No major safety concerns or drug interactions have been reported for Pseudognaphalium obtusifolium thus far.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Ruta chalepensis methanol extract showed cytotoxic activity against HEP-G2 cells with a selectivity index of 291.50.
- Most extracts showed low hemolytic activity and did not present significant toxicity in cell cultures.
- Bee Shannon's and Simpson's diversities were higher in the Rhododendron removal watershed two years after treatment, but benefits weakened one year post-fire.
- The methanol extract from Justicia spicigera showed the highest tumor cell growth inhibition with an IC50 of 29.10 µg/mL.
Frequently asked questions
What is Catfoot?
Catfoot (Pseudognaphalium obtusifolium) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Catfoot?
4 sourced findings are recorded for Catfoot; the strongest carries evidence grade D. For example: Ruta chalepensis methanol extract showed cytotoxic activity against HEP-G2 cells with a selectivity index of 291.50.
How strong is the evidence for Catfoot?
The strongest finding for Catfoot carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Catfoot safe? What are the side effects?
No major safety issues are recorded for Catfoot in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Catfoot interact with medications?
No drug interactions are recorded for Catfoot in our sources. This does not rule them out — check with a pharmacist.
Is Catfoot a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Effects of Rhododendron removal and prescribed fire on bees and plants in the southern Appalachians. literature abstract metadata
- T2 In Vitro Cytotoxic Activity of Methanol Extracts of Selected Medicinal Plants Traditionally Used in Mexico against Human Hepatocellular Carcinoma. literature abstract metadata
- T2 In Vitro Biological Activity and Lymphoma Cell Growth Inhibition by Selected Mexican Medicinal Plants. literature abstract metadata
- T2 In Vitro Evaluation of Anti-Hemolytic and Cytotoxic Effects of Traditional Mexican Medicinal Plant Extracts on Human Erythrocytes and Cell Cultures. literature abstract metadata