Northeast Asian pasque-flower
Pulsatilla chinensis
Pulsatilla chinensis, a traditional Chinese medicinal plant, has been studied for its potential health benefits. While there are no specific recorded traditional uses of this plant in any known traditions, recent scientific research has shown promising results. Studies indicate that anemoside B4 from Pulsatilla chinensis may have anti-inflammatory and immune-modulating effects, as well as the ability to restore gut microbial balance, which could be beneficial for dogs with antibiotic-associated diarrhea. Additionally, 23-hydroxybetulinic acid from this plant has shown potential in inhibiting esophageal cancer cell proliferation through mechanisms involving BUB1 and STAT3 signaling pathways. However, these findings are preliminary and more research is needed to confirm the full scope of its effects. Safety-wise, no major issues have been recorded for Pulsatilla chinensis. There are also currently no known drug interactions associated with this plant. Nonetheless, further investigation is warranted to fully understand any potential risks or interactions that may arise in broader clinical applications.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study identifies four core mechanistic axes of anemoside B4's actions in Pulsatilla chinensis, highlighting context-dependent regulation.
- Pulsatilla chinensis treatment reduced pro-inflammatory cytokines, elevated immune markers, and restored gut microbial diversity in dogs with antibiotic-associated diarrhea.
- Pulsatilla chinensis extract enhanced autophagic flux, reduced Tau phosphorylation, and improved mitochondrial function in neuronal cells and C. elegans models.
- 23-hydroxybetulinic acid from Pulsatilla chinensis inhibited esophageal cancer cell proliferation and induced G2/M phase arrest via downregulating BUB1 and STAT3 signaling.
- HSC-4, a C-28 carboxyl derivative of Hederacoside C, showed significant anti-inflammatory efficacy in murine models without causing hepatotoxicity or nephrotoxicity.
Frequently asked questions
What is Northeast Asian pasque-flower?
Northeast Asian pasque-flower (Pulsatilla chinensis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Northeast Asian pasque-flower?
5 sourced findings are recorded for Northeast Asian pasque-flower; the strongest carries evidence grade D. For example: The study identifies four core mechanistic axes of anemoside B4's actions in Pulsatilla chinensis, highlighting context-dependent regulation.
How strong is the evidence for Northeast Asian pasque-flower?
The strongest finding for Northeast Asian pasque-flower carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Northeast Asian pasque-flower safe? What are the side effects?
No major safety issues are recorded for Northeast Asian pasque-flower in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Northeast Asian pasque-flower interact with medications?
No drug interactions are recorded for Northeast Asian pasque-flower in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Northeast Asian pasque-flower?
Northeast Asian pasque-flower is also known as: Прострел китайский, Pulsatille de Chine.
Is Northeast Asian pasque-flower a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Targeted degradation of aberrant Tau for the discovery of Pulsatilla chinensis in Alzheimer's disease. literature abstract metadata
- T2 23-hydroxybetulinic acid induces cell cycle arrest in esophageal cancer cells via the BUB1/STAT3 signaling pathway. literature abstract metadata
- T2 Integrated Multi-Omics Analysis Explores the Protective Effects and Potential Mechanisms of Pulsatilla chinensis on Canine Antibiotic-Associated Diarrhea. literature abstract metadata
- T2 Decoding anemoside B4: Core mechanistic axes and an omics-to-atom paradigm. literature abstract metadata
- T2 Design, synthesis, and biological evaluation of C-28 carboxyl derivatives of Hederacoside C as anti-inflammatory agents for acute lung injury. literature abstract metadata