Ave Grace
Ruta graveolens
Ruta graveolens, commonly known as rue or garden rue, is a traditional plant that has been used in various herbal practices. While its specific traditional uses are not well-documented, it has shown promise in scientific research for its potential antimicrobial properties and chemical compositions. Studies have demonstrated that extracts from Ruta graveolens leaves can enhance the antimicrobial activity of chitosan films when combined with TiO2-ZnO nanoparticles. Additionally, an endophytic fungus isolated from the plant was found to produce alternariol, which exhibits potent bactericidal effects against Staphylococcus aureus by targeting bacterial membranes. The seeds of Ruta graveolens contain moderate levels of tocopherols and tocotrienols, with γ-tocotrienol being the predominant tocochromanol, indicating potential antioxidant properties. However, the scientific evidence for these findings is currently limited in scope and strength. No significant safety concerns or known drug interactions have been recorded for Ruta graveolens, but further research is warranted to fully understand its potential benefits and risks.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study found that chitosan films impregnated with TiO2-ZnO nanoparticles synthesized using Ruta graveolens leaf extract showed varying antimicrobial activity against tested bacteria and yeast.
- Alternariol from the endophytic fungus Alternaria sp. S4 derived from Ruta graveolens shows potent bactericidal activity against Staphylococcus aureus by targeting bacterial membranes.
- Ruta graveolens seeds contained moderate levels of tocopherols and tocotrienols, with γ-tocotrienol being the major tocochromanol.
- The study identified chemical compositions and AChE inhibitory potentials of essential oils from grapefruit, henna, and sadab, with grapefruit oil showing the strongest activity.
Frequently asked questions
What is Ave Grace?
Ave Grace (Ruta graveolens) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Ave Grace?
4 sourced findings are recorded for Ave Grace; the strongest carries evidence grade D. For example: The study found that chitosan films impregnated with TiO2-ZnO nanoparticles synthesized using Ruta graveolens leaf extract showed varying antimicrobial activity against tested bacteria and yeast.
How strong is the evidence for Ave Grace?
The strongest finding for Ave Grace carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Ave Grace safe? What are the side effects?
No major safety issues are recorded for Ave Grace in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Ave Grace interact with medications?
No drug interactions are recorded for Ave Grace in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Ave Grace?
Ave Grace is also known as: Рута душистая.
Is Ave Grace a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Alternariol from the endophytic fungus Alternaria sp. S4 acts as a membrane-targeting bactericidal agent against Staphylococcus aureus. literature abstract metadata
- T2 GC-MS-based metabolic profiling of essential oils from Citrus paradisi, Lawsonia inermis, and Ruta graveolens and assessment of their acetylcholinesterase inhibitory potential. literature abstract metadata
- T2 Taxonomy-Dependent Seed Tocochromanol Composition in the Rutaceae Family: Application of Sustainable Approach for Their Extraction. literature abstract metadata
- T2 Evaluation of the Antimicrobial Activity of Bimetallic TiO2-ZnO Nanoparticles Phytosynthesized with Ruta graveolens Extract Supported on a Chitosan Film. literature abstract metadata