Maiden saussurea
Saussurea pulchella
Saussurea pulchella is a plant traditionally associated with certain regions but lacks specific traditional medicinal uses. Scientific studies have identified 149 compounds in this plant, including terpenes and phenolic compounds, some of which showed potential for alleviating ulcerative colitis symptoms in mice. Pulchellamin G from Saussurea pulchella was found to suppress inflammatory responses by inducing HO-1 expression in macrophages. Additionally, seven new sesquiterpene lactones and seven new conjugates were isolated, with some exhibiting cytotoxic activity against certain cancer cell lines. While no major safety issues or drug interactions have been recorded, the current evidence base is limited, and further research is needed to confirm these findings.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study identified 149 compounds in Saussurea pulchella and found it effective in alleviating ulcerative colitis symptoms in mice.
- Pulchellamin G from Saussurea pulchella suppressed LPS-induced inflammatory responses by inducing HO-1 expression in macrophages.
- The study identified seven terpenes and eight phenolic compounds from Saussurea pulchella, with some being first reported in the genus.
- Two new sesquiterpene lactones and seven conjugates were isolated from Saussurea pulchella, with some showing cytotoxic activity against certain cancer cell lines.
Frequently asked questions
What is Maiden saussurea?
Maiden saussurea (Saussurea pulchella) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Maiden saussurea?
4 sourced findings are recorded for Maiden saussurea; the strongest carries evidence grade D. For example: The study identified 149 compounds in Saussurea pulchella and found it effective in alleviating ulcerative colitis symptoms in mice.
How strong is the evidence for Maiden saussurea?
The strongest finding for Maiden saussurea carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Maiden saussurea safe? What are the side effects?
No major safety issues are recorded for Maiden saussurea in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Maiden saussurea interact with medications?
No drug interactions are recorded for Maiden saussurea in our sources. This does not rule them out — check with a pharmacist.
Is Maiden saussurea a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Lignan and terpene constituents from the aerial parts of Saussurea pulchella. literature abstract metadata
- T2 Guaiane sesquiterpene lactones and amino acid-sesquiterpene lactone conjugates from the aerial parts of Saussurea pulchella. literature abstract metadata
- T2 Pulchellamin G, an amino acid-sesquiterpene lactone, from Saussurea pulchella suppresses lipopolysaccharide-induced inflammatory responses via heme oxygenase-1 expression in murine peritoneal macrophages. literature abstract metadata
- T2 Study on the Comprehensive Phytochemicals and the Anti-Ulcerative Colitis Effect of Saussurea pulchella. literature abstract metadata