Common Figwort
Scrophularia nodosa
Scrophularia nodosa, a plant traditionally used in various herbal practices but without specific documented traditional uses, has been the subject of recent scientific investigation. Studies have identified new aza-iridoids and observed their bioconversion within the leaves of this plant. Research indicates that fine powders from Scrophularia nodosa, particularly those with particle sizes ranging from 50 to 180 μm, exhibit enhanced anti-inflammatory activity compared to hydroethanolic extracts. The findings suggest potential in modulating inflammatory responses and supporting wound healing, especially in equine models, without significant cytotoxicity. Additionally, some Scrophularia nodosa extracts showed promise for enhancing the effect of fluconazole against Candida albicans and C. tropicalis strains associated with denture stomatitis. Notably, no major safety issues or drug interactions have been recorded to date, though further research is warranted to fully understand its potential applications and effects.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study synthesized new aza-iridoids and detected their bioconversion in Scrophularia nodosa leaves using molecular networking.
- The study found that fine powders, especially superfine particles (50-100 μm and 100-180 μm), from Scrophularia nodosa showed enhanced anti-inflammatory activity compared to hydroethanolic extracts.
- The study found that Scrophularia nodosa extracts, both individually and combined with others, showed potential in modulating inflammatory responses and supporting wound healing in equine models without significant cytotoxicity.
- The study found that some extracts, including those from Scrophularia nodosa, showed potential for enhancing the effect of fluconazole against Candida albicans and C. tropicalis strains associated with denture stomatitis.
- Scrophularia nodosa was among the plants used, though its specific use is not detailed in this abstract.
Frequently asked questions
What is Common Figwort?
Common Figwort (Scrophularia nodosa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Common Figwort?
5 sourced findings are recorded for Common Figwort; the strongest carries evidence grade D. For example: The study synthesized new aza-iridoids and detected their bioconversion in Scrophularia nodosa leaves using molecular networking.
How strong is the evidence for Common Figwort?
The strongest finding for Common Figwort carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Common Figwort safe? What are the side effects?
No major safety issues are recorded for Common Figwort in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Common Figwort interact with medications?
No drug interactions are recorded for Common Figwort in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Common Figwort?
Common Figwort is also known as: норичник узловатый, Scrophulaire noueuse.
Is Common Figwort a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Increased anti-inflammatory activity and enhanced phytochemical concentrations in superfine powders obtained by controlled differential sieving process from four medicinal plants. literature abstract metadata
- T2 Synthesis of Non-natural Aza-Iridoids via Ynamides and Molecular Networking-Based Tracing of Their In Planta Bioconversion. literature abstract metadata
- T2 Ethnomedicine survey on folk dermatology in Transylvania, Romania. literature abstract metadata
- T2 SCREENING OF MEDICINAL AND AROMATIC PLANTS EXTRACTS FOR THE SYNERGISM WITH FLUCONAZOLE AGAINST CANDIDA ALBICANS AND CANDIDA TROPICALIS FUNGI ASSOCIATED WITH DENTURE STOMATITIS. literature abstract metadata
- T2 Anti-Inflammatory and Regenerative Properties of Herbal Extracts: Wound Management in Equine Models. literature abstract metadata