Solanum nigrum

Solanum nigrum

Black nightshade (Solanum nigrum) is a plant traditionally found in Europe, Asia, and parts of Africa. While it has been used in various folk remedies, no specific traditional uses are documented. Scientific studies have shown that the plant's genetics play a role in saponin synthesis, with some mutants affecting this process differently than others. Additionally, carbon quantum dots derived from black nightshade exhibit promising properties for sensor applications due to their fluorescence characteristics and selectivity. Solanum nigrum has also demonstrated potential in reducing liver fibrosis through regulation of YAP signaling pathways. In agricultural settings, the plant's growth can be enhanced when treated with phosphogypsum and phosphate-solubilizing Bacillus megaterium, which also aids in lead immobilization. No significant safety concerns or known drug interactions have been reported for this plant.

At a glance
Best evidence
D
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • The study found that knockout mutants of SlGAME4 in black nightshade redirect resources towards saponin synthesis, while SlGAME2 is not involved in α-tomatine biosynthesis. D PMID
  • Solanum nigrum-derived carbon quantum dots showed promising fluorescence properties and selectivity for detecting various analytes in sensor applications. D PMID
  • Solamargine reduced liver fibrosis by regulating YAP signaling in hepatic stellate cells and mouse models. D PMID
  • The combined treatment of phosphogypsum and phosphate-solubilizing Bacillus megaterium enhanced lead immobilization and supported Solanum nigrum growth in pot experiments. D PMID

Frequently asked questions

What is Solanum nigrum?

Solanum nigrum (Solanum nigrum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Solanum nigrum?

4 sourced findings are recorded for Solanum nigrum; the strongest carries evidence grade D. For example: The study found that knockout mutants of SlGAME4 in black nightshade redirect resources towards saponin synthesis, while SlGAME2 is not involved in α-tomatine biosynthesis.

How strong is the evidence for Solanum nigrum?

The strongest finding for Solanum nigrum carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Solanum nigrum safe? What are the side effects?

No major safety issues are recorded for Solanum nigrum in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Solanum nigrum interact with medications?

No drug interactions are recorded for Solanum nigrum in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Solanum nigrum?

Solanum nigrum is also known as: паслён чёрный, morelle noire.

Is Solanum nigrum a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 The Role of Two Glycoalkaloid Metabolism Genes in α-Tomatine Biosynthesis and Basal Defence in Tomato. literature abstract metadata
  2. T2 Synergistic immobilization of lead and enhanced Solanum nigrum growth by phosphogypsum coupled with phosphate-solubilizing Bacillus megaterium: Roles of Pb mineral transformation and rhizosphere microbiome restructuring. literature abstract metadata
  3. T2 Solamargine alleviates liver fibrosis by regulating YAP signaling in hepatic stellate cells. literature abstract metadata
  4. T2 Biomass based carbon quantum dots in sensor applications: a review (2021-2025). literature abstract metadata