Seashore sowthistle
Sonchus brachyotus
Sonchus brachyotus is a plant traditionally used with limited documentation. Scientific evidence suggests that supplementation with Sonchus brachyotus DC. (SBE) may modulate gut microbiota and key metabolites, reducing oxidative stress in mice subjected to acute ethanol-induced stress. Additionally, combining SBE extracts with synbiotics showed greater effectiveness in preventing and treating non-alcoholic fatty liver disease compared to using either component alone. SBE can reduce reactive oxygen species (ROS) and malondialdehyde (MDA) levels while increasing superoxide dismutase (SOD) and catalase (CAT) activities, potentially through modulating the Nrf2-Keap1-ARE pathway. In mouse models, a herbal mixture containing Sonchus brachyotus (PV-1) inhibited tumor development and remodeled the tumor immune microenvironment. No major safety issues or recorded drug interactions have been noted for SBE to date.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Supplementation with SBE modulates gut microbiota and key metabolites, reducing oxidative stress in ethanol-induced acute stress mice.
- The study found that combining Sonchus brachyotus DC. extracts and synbiotics showed greater effectiveness in preventing and treating non-alcoholic fatty liver disease compared to using either component alone.
- SBE can reduce ROS and MDA levels and increase SOD and CAT activities, potentially through modulating genes in the Nrf2-Keap1-ARE pathway.
- PV-1, a herbal mixture including Sonchus brachyotus, inhibited tumor development and remodeled the tumor immune microenvironment in mouse models.
Frequently asked questions
What is Seashore sowthistle?
Seashore sowthistle (Sonchus brachyotus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Seashore sowthistle?
4 sourced findings are recorded for Seashore sowthistle; the strongest carries evidence grade D. For example: Supplementation with SBE modulates gut microbiota and key metabolites, reducing oxidative stress in ethanol-induced acute stress mice.
How strong is the evidence for Seashore sowthistle?
The strongest finding for Seashore sowthistle carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Seashore sowthistle safe? What are the side effects?
No major safety issues are recorded for Seashore sowthistle in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Seashore sowthistle interact with medications?
No drug interactions are recorded for Seashore sowthistle in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Seashore sowthistle?
Seashore sowthistle is also known as: Осот короткоухий.
Is Seashore sowthistle a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 The Effect of Preventing Oxidative Stress and Its Mechanisms in the Extract from Sonchus brachyotus DC. Based on the Nrf2-Keap1-ARE Signaling Pathway. literature abstract metadata
- T2 Benefits of Combining Sonchus brachyotus DC. Extracts and Synbiotics in Alleviating Non-Alcoholic Fatty Liver Disease. literature abstract metadata
- T2 Cancer chemoprevention with PV-1, a novel Prunella vulgaris-containing herbal mixture that remodels the tumor immune microenvironment in mice. literature abstract metadata
- T2 Regulation on microbial composition,serotonergic synapse, and apoptotic signaling pathway by extracts fromSonchus brachyotus DC. (SBE) to improve ethanol-induced acute oxidative stress in mice. literature abstract metadata