East Himalayan Yew
Taxus wallichiana
Taxus wallichiana, a coniferous tree native to China, is not traditionally used in any known medical practices. Scientific research has identified 11 potential HMGB1 inhibitors from Taxus wallichiana var. mairei using an immobilized HMGB1 method, with sciadopitysin showing significant binding affinity and inhibitory activity. Additionally, Salvia miltiorrhiza hairy roots were engineered to produce taxadiene and protopanaxadiol, indicating potential for scalable production of valuable plant-derived compounds. The distribution of four Taxus species in China under future climate scenarios suggests varied expansion patterns with shifts towards higher latitudes. No major safety issues or drug interactions have been recorded for this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study identified 11 potential HMGB1 inhibitors from Taxus wallichiana var. mairei using an immobilized HMGB1 method, with sciadopitysin showing significant binding affinity and inhibitory activity.
- Salvia miltiorrhiza hairy roots were engineered to produce taxadiene and protopanaxadiol, showing potential for scalable production of valuable plant-derived compounds.
- The suitable distribution areas of four Taxus species in China are predicted to shift and change under future climate scenarios, with varying outcomes for different species.
- The study found that nomadic settlements and non-timber forest product extraction significantly threaten the distribution of Trillium govanianum populations in the Kashmir Himalayas.
Frequently asked questions
What is East Himalayan Yew?
East Himalayan Yew (Taxus wallichiana) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about East Himalayan Yew?
4 sourced findings are recorded for East Himalayan Yew; the strongest carries evidence grade D. For example: The study identified 11 potential HMGB1 inhibitors from Taxus wallichiana var. mairei using an immobilized HMGB1 method, with sciadopitysin showing significant binding affinity and inhibitory activity.
How strong is the evidence for East Himalayan Yew?
The strongest finding for East Himalayan Yew carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is East Himalayan Yew safe? What are the side effects?
No major safety issues are recorded for East Himalayan Yew in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does East Himalayan Yew interact with medications?
No drug interactions are recorded for East Himalayan Yew in our sources. This does not rule them out — check with a pharmacist.
What are the common names of East Himalayan Yew?
East Himalayan Yew is also known as: Тис Валлиха, If de Wallich.
Is East Himalayan Yew a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Geographic distribution patterns, population dynamics, and habitat vulnerability of endangered and endemic Trillium govanianum. literature abstract metadata
- T2 Simulated Assessment of the Impact of Climate Change on the Potential Distribution Range of Four Taxus Species in China. literature abstract metadata
- T2 Engineering Salvia miltiorrhiza hairy roots as a scalable platform for high-yield production of paclitaxel and ginsenoside precursors. literature abstract metadata
- T2 Oriented Immobilization Coupled With Ligand Fishing Strategy for Rapid Discovery of Direct HMGB1 Inhibitors in Taxus wallichiana var. mairei. literature abstract metadata