Lesser Meadow-Rue
Thalictrum minus
Thalictrum minus is a plant native to Europe and Asia, where it has been traditionally used in various herbal practices. While specific traditional uses for this plant are not well-documented, its close relatives have been employed in folk medicine. Scientific evidence suggests that Thalictrum minus may offer protection against lung injury induced by lipopolysaccharides (LPS) through mechanisms involving oxidative stress and inflammatory pathways, similar to other treatments like TML. Additionally, the plant has shown moderate nematicidal activity against S. papillosus larvae, with an LC50 value of 0.070-0.079%. The first complete plastome sequence for Thalictrum aquilegiifolium var. sibiricum was reported and found to cluster with T. minus in phylogenomic analysis. Safety concerns are currently not well-documented, and no major issues have been recorded. There is also no evidence of significant drug interactions associated with this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- ISO treatment significantly protected mice from LPS-induced ALI, similar to TML, by modulating oxidative stress and inflammatory pathways.
- An ABCB-type transporter, AmABCB1, was identified from Argemone mexicana seeds and shown to have activities with sanguinarine and berberine.
- Thalictrum minus showed moderate nematicidal activity against S. papillosus larvae with an LC50 of 0.070-0.079%.
- The study reports the first complete plastome sequence of Thalictrum aquilegiifolium var. sibiricum, which clusters with Thalictrum minus in phylogenomic analysis.
Frequently asked questions
What is Lesser Meadow-Rue?
Lesser Meadow-Rue (Thalictrum minus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Lesser Meadow-Rue?
4 sourced findings are recorded for Lesser Meadow-Rue; the strongest carries evidence grade D. For example: ISO treatment significantly protected mice from LPS-induced ALI, similar to TML, by modulating oxidative stress and inflammatory pathways.
How strong is the evidence for Lesser Meadow-Rue?
The strongest finding for Lesser Meadow-Rue carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Lesser Meadow-Rue safe? What are the side effects?
No major safety issues are recorded for Lesser Meadow-Rue in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Lesser Meadow-Rue interact with medications?
No drug interactions are recorded for Lesser Meadow-Rue in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Lesser Meadow-Rue?
Lesser Meadow-Rue is also known as: Василистник малый.
Is Lesser Meadow-Rue a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Nematicidal activity of aqueous tinctures of plants against larvae of the nematode Strongyloides papillosus. literature abstract metadata
- T2 AmABCB1, an alkaloid transporter from seeds of Argemone mexicana L (Papaveraceae). literature abstract metadata
- T2 Isoorientin protects lipopolysaccharide-induced acute lung injury in mice via modulating Keap1/Nrf2-HO-1 and NLRP3 inflammasome pathways. literature abstract metadata
- T2 Characterization of the complete plastome of Thalictrum aquilegiifolium var. sibiricum (Ranunculaceae), an annual herb. literature abstract metadata