Thalictrum simplex
Thalictrum simplex
Thalictrum simplex is a plant traditionally used in some herbal practices, though specific uses are not well-documented. Scientific research has shown that compounds from this plant have demonstrated anti-cancer properties, with Hernandezine inhibiting liver cancer cell proliferation through G0/G1 phase arrest and apoptosis induction. Additionally, (-)-thalimonine exhibited selective inhibition of influenza virus A/H7N7 and A/H7N1 reproduction in chicken embryo fibroblasts. Bacteriological studies revealed the isolation of a novel bacterium, Paenibacillus thalictri sp. nov., from Thalictrum simplex. The safety profile appears to be favorable with no major issues recorded; however, comprehensive clinical trials are limited. There is currently no evidence suggesting significant drug interactions, but further research is needed to fully understand its potential effects and applications.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Hernandezine from Thalictrum simplex significantly inhibited the proliferation of liver cancer cells by inducing G0/G1 phase arrest and promoting apoptosis.
- Two new pavine alkaloids were isolated from Thalictrum simplex along with a known compound.
- (-)-thalimonine from Thalictrum simplex showed selective inhibition of influenza virus A/H7N7 and A/H7N1 reproduction in chicken embryo fibroblasts.
- A novel bacterium, Paenibacillus thalictri sp. nov., was isolated from Thalictrum simplex.
- The study identified 256 plant species in the Irtysh River Basin valley forests, with 88.67% recognized as resource plants.
Frequently asked questions
What is Thalictrum simplex?
Thalictrum simplex (Thalictrum simplex) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Thalictrum simplex?
5 sourced findings are recorded for Thalictrum simplex; the strongest carries evidence grade D. For example: Hernandezine from Thalictrum simplex significantly inhibited the proliferation of liver cancer cells by inducing G0/G1 phase arrest and promoting apoptosis.
How strong is the evidence for Thalictrum simplex?
The strongest finding for Thalictrum simplex carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Thalictrum simplex safe? What are the side effects?
No major safety issues are recorded for Thalictrum simplex in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Thalictrum simplex interact with medications?
No drug interactions are recorded for Thalictrum simplex in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Thalictrum simplex?
Thalictrum simplex is also known as: Василистник простой, Pigamon simple.
Is Thalictrum simplex a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 In vitro anti-influenza virus activity of the pavine alkaloid (-)-thalimonine isolated from Thalictrum simplex L. literature abstract metadata
- T2 Two New Pavine Alkaloids from Thalictrum simplex. literature abstract metadata
- T2 Paenibacillus thalictri sp. nov., isolated from surface-sterilized tissue of Thalictrum simplex L. literature abstract metadata
- T2 Inhibitory Effect of Hernandezine on the Proliferation of Hepatocellular Carcinoma. literature abstract metadata
- T2 Unique Plant Resources and Distribution Patterns in the Valley Forest of the Irtysh River Basin. literature abstract metadata