Korean mistletoe
Viscum coloratum
Viscum coloratum, commonly known as European mistletoe, is a traditional medicine plant traditionally associated with folk remedies in Europe. While its specific uses are not well-documented historically, studies have shown that Viscum coloratum extract may inhibit RANKL-induced osteoclast differentiation through the PI3K/AKT/mTOR pathway and has been identified to contain 68 differential metabolites, including phenylpropanoids, polyketides, lipids, and organic acids. These findings suggest potential therapeutic applications but are currently limited by the need for further research to confirm these effects in clinical settings. Four quality markers (VIS, HOG, OLA, CHL) have been identified to enhance its quality control in clinical applications. Viscum coloratum polysaccharide has shown promise in ameliorating hyperuricemic nephropathy by upregulating Nrf2 and inhibiting TGF-β1/Smad3 and NLRP3/ASC/Caspase-1 pathways, though the evidence is still emerging. No major safety issues or drug interactions have been recorded to date.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Viscum coloratum extract inhibited RANKL-induced osteoclast differentiation through the PI3K/AKT/mTOR pathway.
- The study found that Viscum coloratum exhibits host-dependent metabolic variations, with 68 annotated differential constituents identified.
- Four potential quality markers (viscumneoside III, homoeriodictyol-7-O-β-glucoside, oleanolic acid, and chlorogenic acid) were identified for Viscum coloratum.
- Viscum coloratum polysaccharide ameliorates hyperuricemic nephropathy by upregulating Nrf2 to inhibit the NLRP3/ASC/Caspase-1 and TGF-β1/Smad3 pathways.
Frequently asked questions
What is Korean mistletoe?
Korean mistletoe (Viscum coloratum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Korean mistletoe?
4 sourced findings are recorded for Korean mistletoe; the strongest carries evidence grade D. For example: Viscum coloratum extract inhibited RANKL-induced osteoclast differentiation through the PI3K/AKT/mTOR pathway.
How strong is the evidence for Korean mistletoe?
The strongest finding for Korean mistletoe carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Korean mistletoe safe? What are the side effects?
No major safety issues are recorded for Korean mistletoe in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Korean mistletoe interact with medications?
No drug interactions are recorded for Korean mistletoe in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Korean mistletoe?
Korean mistletoe is also known as: Омела окрашенная.
Is Korean mistletoe a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Unveiling the Q-Markers of Viscum coloratum (Kom.) Nakai: Enhancing Clinical Efficacy for the Treatment of Rheumatoid Arthritis. literature abstract metadata
- T2 Viscum coloratum polysaccharide ameliorates hyperuricemic nephropathy by upregulating Nrf2 to inhibit TGF-β1/Smad3 and NLRP3/ASC/Caspase-1 pathways. literature abstract metadata
- T2 Viscum coloratum (Kom.) Nakai inhibits osteoclastogenesis in RANKL-induced osteoclast differentiation through the PI3K/AKT/mTOR pathway. literature abstract metadata
- T2 Host-Dependent Metabolomic Variations in Viscum coloratum Revealed by UHPLC-Q-TOF-MS/MS and Integrated Annotation Strategies. literature abstract metadata