African milkbush
Euphorbia tirucalli
Euphorbia tirucalli, commonly known as milk bush or chandana, is a plant native to tropical regions of Africa and Asia. While it has cultural significance in some traditional practices, no specific traditional uses have been recorded for this species. Scientific studies indicate that Euphorbia tirucalli stem extracts exhibit cytotoxic activity against breast cancer cells, with lupeol and β-amyrin showing strong binding affinities to relevant targets. Additionally, the latex of the plant has shown varying antimicrobial activities against different strains of Klebsiella pneumoniae, and its compounds have been found to be effective in inhibiting α-glucosidase activity. The cytotoxicity and antioxidant properties observed suggest potential applications in cancer therapy and diabetes management, though more research is needed to confirm these findings. Safety data for Euphorbia tirucalli does not indicate any major issues; however, the consumption of its latex has been shown to alter cardiac hemodynamics and increase oxidative stress without affecting blood pressure in rats. No significant drug interactions have been recorded as of current knowledge.
- Mejor evidencia
- D
- Precauciones
- —
Solo información. El uso tradicional no significa eficacia probada. La evidencia y la seguridad varían — consulte las fuentes citadas.
Lo que dice la ciencia
- Los extractos de Euphorbia tirucalli mostraron actividad citotóxica y antioxidante contra células del cáncer de mama, con lupeol y β-amirina exhibiendo fuertes afinidades de ligazón a los objetivos relevantes.
- La ingesta de látex de Euphorbia tirucalli en ratas alteró las hemodinámicas cardíacas y aumentó el estrés oxidativo sin cambiar la presión arterial.
- El estudio identificó 25 compuestos de Euphorbia tirucalli vietnamita y encontró que su extracto PE es el más efectivo contra las células Jurkat con un IC50 de 22,38 μg.mL-1.
- El látex de Euphorbia tirucalli contiene compuestos con actividades antimicrobianas variables contra diferentes cepas de Klebsiella pneumoniae.
Frequently asked questions
What is African milkbush?
African milkbush (Euphorbia tirucalli) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about African milkbush?
4 sourced findings are recorded for African milkbush; the strongest carries evidence grade D. For example: Los extractos de Euphorbia tirucalli mostraron actividad citotóxica y antioxidante contra células del cáncer de mama, con lupeol y β-amirina exhibiendo fuertes afinidades de ligazón a los objetivos relevantes.
How strong is the evidence for African milkbush?
The strongest finding for African milkbush carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is African milkbush safe? What are the side effects?
No major safety issues are recorded for African milkbush in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does African milkbush interact with medications?
No drug interactions are recorded for African milkbush in our sources. This does not rule them out — check with a pharmacist.
What are the common names of African milkbush?
African milkbush is also known as: Молочай тирукалли, Bois de lait.
Is African milkbush a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Fuentes
- T2 GC-MS metabolite profiling and multi-target Docking analysis of Calotropis procera and Euphorbia tirucalli stem extracts for cytotoxicity and antioxidant activity. literature abstract metadata
- T2 Further constituents and bioactivities of Vietnamese Euphorbia tirucalli L. literature abstract metadata
- T2 Phytochemical profiling of Euphorbia tirucalli Linn. latex and evaluation of its in vitro antibacterial activity against resistant Klebsiella pneumoniae: an integrative network pharmacology and molecular dynamics simulation study. literature abstract metadata
- T2 Euphorbia tirucalli Latex Ingestion Modifies Heart Function and Increases Myocyte Levels of Oxidative Stress in Normotensive Rats. literature abstract metadata