Bois de lait

Euphorbia tirucalli · African milkbush

Euphorbia tirucalli, commonly known as milk bush or chandana, is a plant native to tropical regions of Africa and Asia. While it has cultural significance in some traditional practices, no specific traditional uses have been recorded for this species. Scientific studies indicate that Euphorbia tirucalli stem extracts exhibit cytotoxic activity against breast cancer cells, with lupeol and β-amyrin showing strong binding affinities to relevant targets. Additionally, the latex of the plant has shown varying antimicrobial activities against different strains of Klebsiella pneumoniae, and its compounds have been found to be effective in inhibiting α-glucosidase activity. The cytotoxicity and antioxidant properties observed suggest potential applications in cancer therapy and diabetes management, though more research is needed to confirm these findings. Safety data for Euphorbia tirucalli does not indicate any major issues; however, the consumption of its latex has been shown to alter cardiac hemodynamics and increase oxidative stress without affecting blood pressure in rats. No significant drug interactions have been recorded as of current knowledge.

En bref
Meilleure preuve
D
Précautions

Information uniquement. L'usage traditionnel ne signifie pas une efficacité prouvée. Les preuves et la sécurité varient — consultez les sources citées.

Ce que dit la science

  • Les extraits de Euphorbia tirucalli ont montré une activité cytotoxique et antioxydante contre les cellules du cancer du sein, avec le lupeol et le β-amyrine exhibant des affinités fortes pour les cibles pertinentes. D PMID
  • L'ingestion de latex d'Euphorbia tirucalli chez les rats a modifié les hémodynamiques cardiaques et augmenté le stress oxydatif sans modifier la pression artérielle. D PMID
  • L'étude a identifié 25 composés chez l'Euphorbia tirucalli vietnamienne et a trouvé que son extrait PE est le plus efficace contre les cellules Jurkat avec un IC50 de 22,38 μg.mL-1. D PMID
  • Le latex d'Euphorbia tirucalli contient des composés ayant différentes activités antibactériennes contre différents souches de Klebsiella pneumoniae. D PMID

Frequently asked questions

What is Bois de lait?

Bois de lait (Euphorbia tirucalli) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Bois de lait?

4 sourced findings are recorded for Bois de lait; the strongest carries evidence grade D. For example: Les extraits de Euphorbia tirucalli ont montré une activité cytotoxique et antioxydante contre les cellules du cancer du sein, avec le lupeol et le β-amyrine exhibant des affinités fortes pour les cibles pertinentes.

How strong is the evidence for Bois de lait?

The strongest finding for Bois de lait carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Bois de lait safe? What are the side effects?

No major safety issues are recorded for Bois de lait in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Bois de lait interact with medications?

No drug interactions are recorded for Bois de lait in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Bois de lait?

Bois de lait is also known as: African milkbush, Молочай тирукалли.

Is Bois de lait a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 GC-MS metabolite profiling and multi-target Docking analysis of Calotropis procera and Euphorbia tirucalli stem extracts for cytotoxicity and antioxidant activity. literature abstract metadata
  2. T2 Further constituents and bioactivities of Vietnamese Euphorbia tirucalli L. literature abstract metadata
  3. T2 Phytochemical profiling of Euphorbia tirucalli Linn. latex and evaluation of its in vitro antibacterial activity against resistant Klebsiella pneumoniae: an integrative network pharmacology and molecular dynamics simulation study. literature abstract metadata
  4. T2 Euphorbia tirucalli Latex Ingestion Modifies Heart Function and Increases Myocyte Levels of Oxidative Stress in Normotensive Rats. literature abstract metadata