African milkbush
Euphorbia tirucalli
Euphorbia tirucalli, commonly known as milk bush or chandana, is a plant native to tropical regions of Africa and Asia. While it has cultural significance in some traditional practices, no specific traditional uses have been recorded for this species. Scientific studies indicate that Euphorbia tirucalli stem extracts exhibit cytotoxic activity against breast cancer cells, with lupeol and β-amyrin showing strong binding affinities to relevant targets. Additionally, the latex of the plant has shown varying antimicrobial activities against different strains of Klebsiella pneumoniae, and its compounds have been found to be effective in inhibiting α-glucosidase activity. The cytotoxicity and antioxidant properties observed suggest potential applications in cancer therapy and diabetes management, though more research is needed to confirm these findings. Safety data for Euphorbia tirucalli does not indicate any major issues; however, the consumption of its latex has been shown to alter cardiac hemodynamics and increase oxidative stress without affecting blood pressure in rats. No significant drug interactions have been recorded as of current knowledge.
- Beste Evidenz
- D
- Warnhinweise
- —
Nur zur Information. Traditionelle Anwendung bedeutet keine nachgewiesene Wirksamkeit. Evidenz und Sicherheit variieren — siehe die angegebenen Quellen.
Was die Wissenschaft sagt
- Extrakte aus dem Stamm von Euphorbia tirucalli zeigten cytotokses und antioxidatives Verhalten gegenüber Brustkrebszellen, wobei Lupeol und β-Amyrin starke Bindungsnäherungen an relevante Ziele aufwiesen.
- Die Verabreichung von Euphorbia tirucalli-Latex an Ratten änderte die kardialen Hemodynamik und verstärkte den氧化剂自由基水平而不改变血压。
- Die Studie identifizierte 25 Verbindungen bei Euphorbia tirucalli aus Vietnam und fand heraus, dass sein PE-Auflösung am effektivsten gegen Jurkat-Zellen ist mit einem IC50 von 22,38 μg.mL-1.
- Das Latex von Euphorbia tirucalli enthält Stoffe mit variierenden antimikrobiellen Aktivitäten gegen verschiedene Stränge von Klebsiella pneumoniae.
Frequently asked questions
What is African milkbush?
African milkbush (Euphorbia tirucalli) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about African milkbush?
4 sourced findings are recorded for African milkbush; the strongest carries evidence grade D. For example: Extrakte aus dem Stamm von Euphorbia tirucalli zeigten cytotokses und antioxidatives Verhalten gegenüber Brustkrebszellen, wobei Lupeol und β-Amyrin starke Bindungsnäherungen an relevante Ziele aufwiesen.
How strong is the evidence for African milkbush?
The strongest finding for African milkbush carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is African milkbush safe? What are the side effects?
No major safety issues are recorded for African milkbush in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does African milkbush interact with medications?
No drug interactions are recorded for African milkbush in our sources. This does not rule them out — check with a pharmacist.
What are the common names of African milkbush?
African milkbush is also known as: Молочай тирукалли, Bois de lait.
Is African milkbush a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Quellen
- T2 GC-MS metabolite profiling and multi-target Docking analysis of Calotropis procera and Euphorbia tirucalli stem extracts for cytotoxicity and antioxidant activity. literature abstract metadata
- T2 Further constituents and bioactivities of Vietnamese Euphorbia tirucalli L. literature abstract metadata
- T2 Phytochemical profiling of Euphorbia tirucalli Linn. latex and evaluation of its in vitro antibacterial activity against resistant Klebsiella pneumoniae: an integrative network pharmacology and molecular dynamics simulation study. literature abstract metadata
- T2 Euphorbia tirucalli Latex Ingestion Modifies Heart Function and Increases Myocyte Levels of Oxidative Stress in Normotensive Rats. literature abstract metadata