African milkbush

Euphorbia tirucalli, commonly known as milk bush or chandana, is a plant native to tropical regions of Africa and Asia. While it has cultural significance in some traditional practices, no specific traditional uses have been recorded for this species. Scientific studies indicate that Euphorbia tirucalli stem extracts exhibit cytotoxic activity against breast cancer cells, with lupeol and β-amyrin showing strong binding affinities to relevant targets. Additionally, the latex of the plant has shown varying antimicrobial activities against different strains of Klebsiella pneumoniae, and its compounds have been found to be effective in inhibiting α-glucosidase activity. The cytotoxicity and antioxidant properties observed suggest potential applications in cancer therapy and diabetes management, though more research is needed to confirm these findings. Safety data for Euphorbia tirucalli does not indicate any major issues; however, the consumption of its latex has been shown to alter cardiac hemodynamics and increase oxidative stress without affecting blood pressure in rats. No significant drug interactions have been recorded as of current knowledge.

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.