Chinese-foxglove
Rehmannia glutinosa
Rehmannia glutinosa, a traditional Chinese medicinal plant also known as dihuang, is used in various herbal remedies. Its use primarily revolves around its purported benefits for blood and yin tonification, although specific traditional uses are not extensively documented. Scientific evidence suggests potential health benefits such as preventing estrogen-deficiency-induced osteoporosis through mechanisms involving the inhibition of osteoclastogenesis and induction of their apoptosis. Additionally, Rehmannia glutinosa has shown promise in suppressing colorectal cancer cell proliferation via a NCOA4/FTH1 pathway activation mechanism. The Taohong Siwu Decoction derived from this plant has identified six key components that may serve as quality markers for its antithrombotic effects. Furthermore, Rehmannia glutinosa treatment improved cognitive functions and reduced neuronal loss in mice subjected to traumatic brain injury (TBI) by suppressing microglial activation. To date, no significant safety concerns or drug interactions have been recorded with this plant.
- Mejor evidencia
- D
- Precauciones
- —
Solo información. El uso tradicional no significa eficacia probada. La evidencia y la seguridad varían — consulte las fuentes citadas.
Lo que dice la ciencia
- El tratamiento con REA mejoró las funciones cognitivas y redujo la pérdida neuronal en ratones con TBI inhibiendo la activación microglial.
- Rehmanniosido D previene la osteoporosis inducida por la deficiencia de estrógenos inhibiendo la osteoclastogénesis y promoviendo su apoptosis a través de dos mecanismos.
- SWHQD suprime el cáncer colorrectal a través de la ferroptosis inducida por la fagocitosis de ferritina mediada por NCOA4/FTH1.
- Este estudio identificó seis componentes clave en la Decocción Taohong Siwu basada en Rehmannia glutinosa como posibles marcadores Q para sus efectos antitrombóticos.
Frequently asked questions
What is Chinese-foxglove?
Chinese-foxglove (Rehmannia glutinosa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Chinese-foxglove?
4 sourced findings are recorded for Chinese-foxglove; the strongest carries evidence grade D. For example: El tratamiento con REA mejoró las funciones cognitivas y redujo la pérdida neuronal en ratones con TBI inhibiendo la activación microglial.
How strong is the evidence for Chinese-foxglove?
The strongest finding for Chinese-foxglove carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Chinese-foxglove safe? What are the side effects?
No major safety issues are recorded for Chinese-foxglove in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Chinese-foxglove interact with medications?
No drug interactions are recorded for Chinese-foxglove in our sources. This does not rule them out — check with a pharmacist.
Is Chinese-foxglove a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Fuentes
- T2 Rehmannioside A alleviates neuroinflammation and cognitive impairments after traumatic brain injury by suppressing microglial activation via the MAPK/NF-κB pathway. literature abstract metadata
- T2 A multidimensional integrated strategy for identifying anti-thrombotic quality markers(Q-Markers) in Taohong Siwu decoction through combined analysis of chemical profiling, bioactivity, and pharmacodynamic efficacy. literature abstract metadata
- T2 Sanwu Huangqin decoction induces ferroptosis in colorectal cancer cells by triggering NCOA4/FTH1-mediated ferritinophagy. literature abstract metadata
- T2 Rehmannioside D prevents estrogen-deficiency induced osteoporosis by interacting with c-Jun to dismantle the AP-1 complex and suppress MAPK/NF-κB signaling. literature abstract metadata