Chinese-foxglove
Rehmannia glutinosa
Rehmannia glutinosa, a traditional Chinese medicinal plant also known as dihuang, is used in various herbal remedies. Its use primarily revolves around its purported benefits for blood and yin tonification, although specific traditional uses are not extensively documented. Scientific evidence suggests potential health benefits such as preventing estrogen-deficiency-induced osteoporosis through mechanisms involving the inhibition of osteoclastogenesis and induction of their apoptosis. Additionally, Rehmannia glutinosa has shown promise in suppressing colorectal cancer cell proliferation via a NCOA4/FTH1 pathway activation mechanism. The Taohong Siwu Decoction derived from this plant has identified six key components that may serve as quality markers for its antithrombotic effects. Furthermore, Rehmannia glutinosa treatment improved cognitive functions and reduced neuronal loss in mice subjected to traumatic brain injury (TBI) by suppressing microglial activation. To date, no significant safety concerns or drug interactions have been recorded with this plant.
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- REA治疗改善了TBI小鼠的认知功能并减少了神经元丢失，通过抑制小胶质细胞激活。
- rehmannioside D 预防雌激素缺乏引起的骨质疏松，通过双重机制抑制成骨细胞生成并诱导其凋亡。
- SWHQD通过NCOA4/FTH1介导的铁蛋白自噬引起的铁死亡来抑制结肠癌。
- 这项研究在基于熟地黄的桃红四物汤中鉴定了六个关键成分作为其抗血栓作用的潜在Q-标志物。
Frequently asked questions
What is Chinese-foxglove?
Chinese-foxglove (Rehmannia glutinosa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Chinese-foxglove?
4 sourced findings are recorded for Chinese-foxglove; the strongest carries evidence grade D. For example: REA治疗改善了TBI小鼠的认知功能并减少了神经元丢失，通过抑制小胶质细胞激活。
How strong is the evidence for Chinese-foxglove?
The strongest finding for Chinese-foxglove carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Chinese-foxglove safe? What are the side effects?
No major safety issues are recorded for Chinese-foxglove in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Chinese-foxglove interact with medications?
No drug interactions are recorded for Chinese-foxglove in our sources. This does not rule them out — check with a pharmacist.
Is Chinese-foxglove a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Rehmannioside A alleviates neuroinflammation and cognitive impairments after traumatic brain injury by suppressing microglial activation via the MAPK/NF-κB pathway. literature abstract metadata
- T2 A multidimensional integrated strategy for identifying anti-thrombotic quality markers(Q-Markers) in Taohong Siwu decoction through combined analysis of chemical profiling, bioactivity, and pharmacodynamic efficacy. literature abstract metadata
- T2 Sanwu Huangqin decoction induces ferroptosis in colorectal cancer cells by triggering NCOA4/FTH1-mediated ferritinophagy. literature abstract metadata
- T2 Rehmannioside D prevents estrogen-deficiency induced osteoporosis by interacting with c-Jun to dismantle the AP-1 complex and suppress MAPK/NF-κB signaling. literature abstract metadata