FolkKB

Chinese-foxglove

Rehmannia glutinosa

Rehmannia glutinosa，一种传统中药植物，在草药疗法中广泛使用，并在东方医学中有悠久的传统。传统上认为它对肾虚和血液疾病有益，尽管具体的用途没有广泛记录。科学证据表明其潜在的好处包括改善认知功能和减少创伤性脑损伤（TBI）后的神经元丢失，通过抑制微胶质细胞激活的机制。此外，Rehmannia glutinosa 还显示出预防雌激素缺乏引起的骨质疏松症的潜力，通过双重机制抑制成骨细胞生成并诱导其凋亡。此外，它似乎具有抗癌作用，特别是针对结直肠癌，通过 NCOA4/FTH1 介导的铁死亡诱导。已确定 Rehmannia glutinosa 基础的 Taohong Siwu 汤剂中的六个关键成分可能是其抗血栓效果的质量标志物。目前没有发现重大安全问题或记录在案的药物相互作用，但进一步的研究是必要的以全面了解其疗效和安全性。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • REA治疗改善了TBI小鼠的认知功能并减少了神经元丢失，通过抑制小胶质细胞激活。 D PMID
  • rehmannioside D 预防雌激素缺乏引起的骨质疏松，通过双重机制抑制成骨细胞生成并诱导其凋亡。 D PMID
  • SWHQD通过NCOA4/FTH1介导的铁蛋白自噬引起的铁死亡来抑制结肠癌。 D PMID
  • 这项研究在基于熟地黄的桃红四物汤中鉴定了六个关键成分作为其抗血栓作用的潜在Q-标志物。 D PMID

Frequently asked questions

What is Chinese-foxglove?

Chinese-foxglove (Rehmannia glutinosa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Chinese-foxglove?

4 sourced findings are recorded for Chinese-foxglove; the strongest carries evidence grade D. For example: REA治疗改善了TBI小鼠的认知功能并减少了神经元丢失，通过抑制小胶质细胞激活。

How strong is the evidence for Chinese-foxglove?

The strongest finding for Chinese-foxglove carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Chinese-foxglove safe? What are the side effects?

No major safety issues are recorded for Chinese-foxglove in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Chinese-foxglove interact with medications?

No drug interactions are recorded for Chinese-foxglove in our sources. This does not rule them out — check with a pharmacist.

Is Chinese-foxglove a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Rehmannioside A alleviates neuroinflammation and cognitive impairments after traumatic brain injury by suppressing microglial activation via the MAPK/NF-κB pathway. literature abstract metadata
  2. T2 A multidimensional integrated strategy for identifying anti-thrombotic quality markers(Q-Markers) in Taohong Siwu decoction through combined analysis of chemical profiling, bioactivity, and pharmacodynamic efficacy. literature abstract metadata
  3. T2 Sanwu Huangqin decoction induces ferroptosis in colorectal cancer cells by triggering NCOA4/FTH1-mediated ferritinophagy. literature abstract metadata
  4. T2 Rehmannioside D prevents estrogen-deficiency induced osteoporosis by interacting with c-Jun to dismantle the AP-1 complex and suppress MAPK/NF-κB signaling. literature abstract metadata