Chinese-foxglove
Rehmannia glutinosa
Rehmannia glutinosa, a traditional Chinese medicinal plant also known as dihuang, is used in various herbal remedies. Its use primarily revolves around its purported benefits for blood and yin tonification, although specific traditional uses are not extensively documented. Scientific evidence suggests potential health benefits such as preventing estrogen-deficiency-induced osteoporosis through mechanisms involving the inhibition of osteoclastogenesis and induction of their apoptosis. Additionally, Rehmannia glutinosa has shown promise in suppressing colorectal cancer cell proliferation via a NCOA4/FTH1 pathway activation mechanism. The Taohong Siwu Decoction derived from this plant has identified six key components that may serve as quality markers for its antithrombotic effects. Furthermore, Rehmannia glutinosa treatment improved cognitive functions and reduced neuronal loss in mice subjected to traumatic brain injury (TBI) by suppressing microglial activation. To date, no significant safety concerns or drug interactions have been recorded with this plant.
- Meilleure preuve
- D
- Précautions
- —
Information uniquement. L'usage traditionnel ne signifie pas une efficacité prouvée. Les preuves et la sécurité varient — consultez les sources citées.
Ce que dit la science
- Le traitement par REA a amélioré les fonctions cognitives et réduit la perte neuronale chez les souris avec TBI en inhibant l'activation microgliale.
- Le rehmannioside D prévient l'ostéoporose due à une déficience en œstrogènes en inhibant l'ostéoclastogénèse et en induisant leur apoptose par deux mécanismes.
- SWHQD réprime le cancer colorectal par voie de ferropthose induite par la phagocytose de ferritine médianée par NCOA4/FTH1.
- Cette étude a identifié six composants clés dans l'infusion Taohong Siwu basée sur Rehmannia glutinosa comme des marqueurs potentiels Q pour ses effets antithrombotiques.
Frequently asked questions
What is Chinese-foxglove?
Chinese-foxglove (Rehmannia glutinosa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Chinese-foxglove?
4 sourced findings are recorded for Chinese-foxglove; the strongest carries evidence grade D. For example: Le traitement par REA a amélioré les fonctions cognitives et réduit la perte neuronale chez les souris avec TBI en inhibant l'activation microgliale.
How strong is the evidence for Chinese-foxglove?
The strongest finding for Chinese-foxglove carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Chinese-foxglove safe? What are the side effects?
No major safety issues are recorded for Chinese-foxglove in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Chinese-foxglove interact with medications?
No drug interactions are recorded for Chinese-foxglove in our sources. This does not rule them out — check with a pharmacist.
Is Chinese-foxglove a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Rehmannioside A alleviates neuroinflammation and cognitive impairments after traumatic brain injury by suppressing microglial activation via the MAPK/NF-κB pathway. literature abstract metadata
- T2 A multidimensional integrated strategy for identifying anti-thrombotic quality markers(Q-Markers) in Taohong Siwu decoction through combined analysis of chemical profiling, bioactivity, and pharmacodynamic efficacy. literature abstract metadata
- T2 Sanwu Huangqin decoction induces ferroptosis in colorectal cancer cells by triggering NCOA4/FTH1-mediated ferritinophagy. literature abstract metadata
- T2 Rehmannioside D prevents estrogen-deficiency induced osteoporosis by interacting with c-Jun to dismantle the AP-1 complex and suppress MAPK/NF-κB signaling. literature abstract metadata