millepertuis
Hypericum
Hypericum is a genus of plants traditionally used in various herbal practices. Hypericum perforatum L., commonly known as St. John's Wort, has been studied for its potential antidepressant effects and is used in some traditional medicine systems to address depressive symptoms. Scientific evidence suggests that both H. perforatum and Chaihu Shugan San may alleviate depressive-like behaviors through different mechanisms but with overlapping pathways. Additionally, research indicates that H. perforatum and Glycyrrhiza glabra can preserve cardiac mitochondrial redox homeostasis in estrogen deficiency by modulating MAO-A and ERβ activity, while H. perforatum and Achillea millefolium essential oils show synergistic antibacterial effects against Staphylococcus epidermidis in specific oil combinations. Hypericum extracts also demonstrated significant sleep-promoting effects in mice, possibly through adenosine and melatonin receptor signaling. No major safety concerns or drug interactions have been recorded for Hypericum use to date.
- Meilleure preuve
- D
- Précautions
- —
Information uniquement. L'usage traditionnel ne signifie pas une efficacité prouvée. Les preuves et la sécurité varient — consultez les sources citées.
Ce que dit la science
- Les deuxHypericum perforatum L. (Saint-Jean-de-Dieu) et Chaihu Shugan San ont atténué les comportements dépressifs par des mécanismes moléculaires distincts mais partiellement chevauchants.
- Hypericum perforatum et Glycyrrhiza glabra préserveraient l'homéostasie rédox mitochondriale cardiaque chez l'insuffisance d'oestrogènes en modulant MAO-A et ERβ.
- Les huiles essentielles d'Hypericum perforatum et d'Achillea millefolium ont montré une activité synergétique contre Staphylococcus epidermidis dans certaines combinaisons d'huile.
- L’HME a réduit significativement le délai d'endormissement et a prolongé le temps total de sommeil chez les souris, suggérant des effets modulés par la signification des récepteurs d'adénosine et de mélatonine.
- L'extrait hydroalcoolique de Hypericum triquetrifolium montre une activité antioxydante et anti-inflammatoire forte, avec une cytopathicité sélective contre les cellules du cancer pancréatique.
Frequently asked questions
What is millepertuis?
millepertuis (Hypericum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about millepertuis?
5 sourced findings are recorded for millepertuis; the strongest carries evidence grade D. For example: Les deuxHypericum perforatum L. (Saint-Jean-de-Dieu) et Chaihu Shugan San ont atténué les comportements dépressifs par des mécanismes moléculaires distincts mais partiellement chevauchants.
How strong is the evidence for millepertuis?
The strongest finding for millepertuis carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is millepertuis safe? What are the side effects?
No major safety issues are recorded for millepertuis in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does millepertuis interact with medications?
No drug interactions are recorded for millepertuis in our sources. This does not rule them out — check with a pharmacist.
What are the common names of millepertuis?
millepertuis is also known as: Зверобой.
Is millepertuis a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Chemical Composition and Synergistic Antimicrobial Activity of Hypericum perforatum and Achillea millefolium Essential Oils Against Wound-Associated Microorganisms. literature abstract metadata
- T2 In Vitro Evidence for the Dual Antioxidant and Anti-Inflammatory Roles of Hypericum triquetrifolium in Cancer Therapy: Selective Cytotoxicity Against Pancreatic Cancer Cells. literature abstract metadata
- T2 Hypericum perforatum L. and Glycyrrhiza glabra L. preserve cardiac mitochondrial redox homeostasis in E2 deficiency via ERβ-MAO-A modulation. literature abstract metadata
- T2 Integrative Proteomics Reveals Distinct Lipid Metabolic and Gut Microbiota-Associated Antidepressant Mechanisms of Two Herbal Medicines in a Chronic Stress Model. literature abstract metadata
- T2 Hypnotic Effects of Hypericum perforatum L. and Melissa officinalis L. Through Adenosine and Melatonin Receptors. literature abstract metadata