Pétasite du Japon
Petasites japonicus · Butterbur
Petasites japonicus, commonly known as Japanese butterburr, is a plant native to East Asia. While its traditional use in medicine has not been extensively documented, it has shown promise in several scientific studies. For instance, pretreatment with Petasites japonicus methanolic extract (PPJM) improved memory deficits and modulated cholinergic function and neuroinflammatory responses in mice. Additionally, extracts from the leaves have demonstrated efficacy in alleviating symptoms of colitis and depression-like behaviors through multiple mechanisms. In a more specific study, administration of butein (BSE), a compound found in Petasites japonicus, significantly extended overall survival in dogs with oral melanoma without affecting progression-free survival. Moreover, topical application of KP-1, derived from the plant, reduced UVB-induced skin damage by decreasing wrinkle formation and epidermal thickening while restoring collagen density. Scientific evidence suggests potential benefits for memory enhancement, colitis relief, depression symptoms, and skin health, though these findings are preliminary and require further investigation. No major safety concerns or drug interactions have been reported to date.
- Meilleure preuve
- D
- Précautions
- —
Information uniquement. L'usage traditionnel ne signifie pas une efficacité prouvée. Les preuves et la sécurité varient — consultez les sources citées.
Ce que dit la science
- L'extrait de feuilles de Petasites japonicus soulage le colite et les comportements dépressifs chez la souris par plusieurs mécanismes.
- Un traitement préalable avec PPJM a amélioré partiellement les déficits de mémoire induits par la scopolamine et a modulé la fonction cholinergique et les réponses neuro-inflammatoires chez les souris.
- KP-1 a réduit les dommages cutanés dus à l'irradiation UVB, notamment les rides et la dégradation du collagène, tout en améliorant l'hydratation de la peau et en activant des voies de signaux protecteurs.
- L'administration de BSE a considérablement prolongé la survie globale, sans cependant allonger la survie sans progression chez les chiens atteints d'un mélanome buccal, et était sûre à administrer.
Frequently asked questions
What is Pétasite du Japon?
Pétasite du Japon (Petasites japonicus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Pétasite du Japon?
4 sourced findings are recorded for Pétasite du Japon; the strongest carries evidence grade D. For example: L'extrait de feuilles de Petasites japonicus soulage le colite et les comportements dépressifs chez la souris par plusieurs mécanismes.
How strong is the evidence for Pétasite du Japon?
The strongest finding for Pétasite du Japon carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Pétasite du Japon safe? What are the side effects?
No major safety issues are recorded for Pétasite du Japon in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Pétasite du Japon interact with medications?
No drug interactions are recorded for Pétasite du Japon in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Pétasite du Japon?
Pétasite du Japon is also known as: Butterbur, Белокопытник японский.
Is Pétasite du Japon a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Anti-Photoaging Effects of a Standardized Hot Water Extract of Petasites japonicus Leaves in Ultraviolet B-Exposed Hairless Mice. literature abstract metadata
- T2 Clinical impact of butterbur shoot extract in dogs with oral melanoma: a combined phase 1 and 2 clinical trial. literature abstract metadata
- T2 Petasites japonicus Leaves Alleviate Depression in Dextran Sulfate Sodium-Induced Colitis Mice Through the BDNF/TrkB Pathway and Modulation of Inflammation. literature abstract metadata
- T2 Protective Effects of a Propolis-Petasites japonicus Mixture on Scopolamine-Induced Memory Impairment in Mice. literature abstract metadata