Scutellaire

Scutellaria · Huachuca Skullcap

Scutellaria is a genus of plants traditionally used in various herbal medicine systems. While specific traditional uses for Scutellaria species are not extensively documented, studies have shown promising results with certain species. For instance, Scutellaria barbata has been investigated for its potential anti-cancer properties, particularly in colorectal and breast cancer models. Scientific evidence suggests that HD-SB treatment can reduce hepatic tumor nodules and suppress epithelial-mesenchymal transition (EMT) in both in vivo and in vitro models of colorectal cancer liver metastasis. Additionally, Scutellaria barbata water extract has been found to inhibit breast cancer growth and lung metastasis by inducing ferroptosis and suppressing EMT without causing systemic toxicity. However, the evidence is still preliminary and more research is needed to confirm these findings. No major safety concerns have been recorded for Scutellaria species; however, due to the limited clinical data, further studies are recommended before widespread use. There are currently no reported drug interactions associated with Scutellaria, but as with any herbal supplement, it is advisable to consult a healthcare provider to ensure there are no potential interactions or contraindications with existing medications.

En bref
Meilleure preuve
B
Précautions

Information uniquement. L'usage traditionnel ne signifie pas une efficacité prouvée. Les preuves et la sécurité varient — consultez les sources citées.

Ce que dit la science

  • Le traitement HD-SB a réduit les nodules tumoraux hépatiques et a supprimé la transition épithélio-mésenchymale dans les modèles both in vivo et in vitro de métastases de cancer colorectal au foie. D PMID
  • L'extrait aquatique de Scutellaria barbata a réduit la croissance du cancer du sein et les métastases pulmonaires en provoquant la ferropthose et en inhibant l'EMT, sans causer de toxicité systémique. D PMID
  • L'étude a identifié des différences métaboliques entre deux spécifications et quatre sources géographiques de Scutellaria baicalensis Georgi en utilisant l'apprentissage automatique. D PMID
  • L'utilisation combinée de Hedyotis diffusa et Scutellaria barbata montre des effets plus marqués contre le carcinome hépatocellulaire que leur utilisation individuelle, bien qu'il soit nécessaire d'effectuer davantage de recherches pour confirmer ces résultats. D PMID
  • L'étude a réussi à utiliser la combinaison SQPCA avec la spectroscopie de corrélation 2T2D pour déterminer semi-quantitativement les concentrations de flavonoïdes dans les racines de Scutellaria baicalensis. D PMID
  • L'étude a montré qu'un usage de la médecine herboriste chinoise était associé à un taux de survie globale sur dix ans significativement plus élevé chez les patients atteints de cancer du sein triplement négatif par rapport aux non-utilisateurs. B PMID
  • L'étude a identifié 25 gènes SbGATA chez Scutellaria baicalensis et a constaté que l'expression du gène SbGATA6 était augmentée par le traitement à la pointe de carbone, tandis que les autres gènes montraient une diminution. D PMID

Frequently asked questions

What is Scutellaire?

Scutellaire (Scutellaria) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Scutellaire?

7 sourced findings are recorded for Scutellaire; the strongest carries evidence grade B. For example: Le traitement HD-SB a réduit les nodules tumoraux hépatiques et a supprimé la transition épithélio-mésenchymale dans les modèles both in vivo et in vitro de métastases de cancer colorectal au foie.

How strong is the evidence for Scutellaire?

The strongest finding for Scutellaire carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).

Is Scutellaire safe? What are the side effects?

No major safety issues are recorded for Scutellaire in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Scutellaire interact with medications?

No drug interactions are recorded for Scutellaire in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Scutellaire?

Scutellaire is also known as: Huachuca Skullcap, Шлемник.

Is Scutellaire a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 Integrative Chinese Herbal Medicine as Adjuvant Management for Triple-Negative Breast Cancer: A Multi-Institutional Real-World Study With Mechanism Exploration. literature abstract metadata
  2. T2 Scutellaria Barbata Water Extract Suppresses Breast Cancer Growth and Lung Metastasis by Inducing Ferroptosis. literature abstract metadata
  3. T2 Hedyotis diffusa Willd-Scutellaria barbata D.Don Suppresses Colorectal Cancer Liver Metastasis by Targeting hsa_circ_0039933-Mediated Epithelial-Mesenchymal Transition. literature abstract metadata
  4. T2 A Comprehensive Review of Hedyotis Diffusa Willd-Scutellaria Barbata D. Don Herb Pair in Anti- Hepatocellular Carcinoma Effects and Their Combinatorial Effects and Mechanisms. literature abstract metadata
  5. T2 Genome-Wide Identification and Expression Pattern Analysis of the GATA Gene Family Members in Scutellaria baicalensis Georgi Under Carbon Dot Treatment. literature abstract metadata
  6. T2 Metabolomics coupled with machine learning highlights metabolite profile differences of Scutellaria baicalensis Georgi from different specifications and geographical origins. literature abstract metadata
  7. T2 EXPRESS: Two-Trace Two-Dimensional (2T2D) Correlation Spectroscopy with Score-Based Quantitative Principal Component Analysis for the Quantification of Multicomponent Chemical Systems Using Attenuated Total Reflection Fourier Transform Infr literature abstract metadata