Hidden-Lily
Curcuma
姜黄，一种传统植物根，在各种文化实践中被广泛使用，特别是在亚洲医学中，但缺乏特定的记录传统。科学证据表明，它可能对良性前列腺增生（BPH）等状况以及某些类型的癌症，特别是三阴性乳腺癌（TNBC），具有潜在益处，通过调节基因表达和靶向细胞作用机制实现。然而，当前的研究受到研究设计多样性和样本量小的限制，使得得出明确结论变得困难。尚未报告姜黄存在显著的安全问题或药物相互作用，但需要进一步研究以全面了解其潜在影响及其应用。
- 最佳证据
- A
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 研究发现，黄芪-莪术组合通过去甲氧基姜黄素调节基因表达并靶向血管内皮细胞。
- 补充姜黄素与男性BPH患者下尿路症状和功能参数的显著改善有关，尽管证据受到异质性和研究设计差异的限制。
- 网络药理学分析表明，姜黄素可能通过靶向AURKA、BRAF（V600E）和CHEK1在TNBC中发挥抗肿瘤作用。
- 姜黄素的代谢转化产生如二氢姜黄素、四氢姜黄素和六氢姜黄素等减少的代谢物，这些代谢物在葡萄糖和脂质代谢中表现出与母体化合物相当的活性。
- 局部递送的姜黄素/姜黄衍生制剂与SRP联合使用可能在某些研究中适度减少牙周袋深度，但由于异质性和方法学限制，结果需谨慎解释。
- 这项研究确定了几个可能由calebin-A在管理肥胖中靶向的基因和途径，包括溶酶体活性、免疫反应和细胞迁移。
- 该研究提供了对姜黄素在NF-κB p50的DNA识别区域附近潜在结合特性的计算表征。
- 双去甲氧基姜黄素诱导自噬，降低了衰老标志物并减少了3xTg-AD小鼠海马区的Aβ负荷。
Frequently asked questions
What is Hidden-Lily?
Hidden-Lily (Curcuma) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Hidden-Lily?
8 sourced findings are recorded for Hidden-Lily; the strongest carries evidence grade A. For example: 研究发现，黄芪-莪术组合通过去甲氧基姜黄素调节基因表达并靶向血管内皮细胞。
How strong is the evidence for Hidden-Lily?
The strongest finding for Hidden-Lily carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Hidden-Lily safe? What are the side effects?
No major safety issues are recorded for Hidden-Lily in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Hidden-Lily interact with medications?
No drug interactions are recorded for Hidden-Lily in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Hidden-Lily?
Hidden-Lily is also known as: Куркума, Curcumas.
Is Hidden-Lily a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Curcumin versus placebo in benign prostatic hyperplasia: a systematic review and meta-analysis. literature abstract metadata
- T2 Local curcumin/turmeric-derived delivery adjunctive to scaling and root planing for periodontitis: a systematic review and meta-analysis. literature abstract metadata
- T2 Integrating Seropharmacology, Network Pharmacology, and Single-Cell Transcriptomics to Decipher the Dual Anti-Tumor Mechanisms of Astragalus-Curcuma zedoaria in Lung Squamous Cell Carcinoma. literature abstract metadata
- T2 AMPK-mediated autophagy induction by bisdemethoxycurcumin attenuates senescence and amyloid pathology in 3xTg-AD mice. literature abstract metadata
- T2 Molecular dynamics and free energy analysis of curcumin binding near the DNA-recognition interface of NF-κB. literature abstract metadata
- T2 Curcumin Metabolites and Metabolic Health: Insights into Regulatory Mechanisms of Glucose and Lipid Homeostasis. literature abstract metadata
- T2 Integrated network pharmacology reveal new key curcumin-binding targets in triple-negative breast cancer. literature abstract metadata
- T2 Exploring the Potential of Calebin-A in Targeting Obesity-Related Genes and Pathways. literature abstract metadata