Hidden-Lily
Curcuma
Curcuma, a traditional plant with roots used in various cultural practices, particularly in Asian medicine, but lacks specific recorded traditions. Scientific evidence suggests potential benefits for conditions such as benign prostatic hyperplasia (BPH) and possibly certain types of cancer, notably triple-negative breast cancer (TNBC), through mechanisms involving gene expression modulation and targeted cellular effects. However, the current body of research is limited by heterogeneity in study designs and small sample sizes, making definitive conclusions challenging. No significant safety concerns or drug interactions have been reported for curcuma, though further studies are needed to fully understand its potential impacts and applications.
- Best evidence
- A
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study found that Astragalus-Curcuma zedoaria combination modulates gene expression and targets vascular endothelial cells via demethoxycurcumin.
- Curcumin supplementation was associated with significant improvement in lower urinary tract symptoms and functional parameters in men with BPH, though evidence is limited by heterogeneity and study design variability.
- Network pharmacology analysis suggests that curcumin may exert antitumor effects in TNBC by targeting AURKA, BRAF (V600E), and CHEK1.
- Curcumin's metabolic transformation results in reduced metabolites like dihydrocurcumin, tetrahydrocurcumin, and hexahydrocurcumin that exhibit comparable activity to the parent compound in glucose and lipid metabolism.
- Locally delivered curcumin/turmeric-derived formulations adjunctively with SRP may modestly reduce periodontal pocket depth in some studies, but findings are cautiously interpreted due to heterogeneity and methodological limitations.
- This study identified several genes and pathways potentially targeted by Calebin-A in managing obesity, including lysosomal activity, immune response, and cell migration.
- The study provides a computational characterization of curcumin's potential binding near the DNA-recognition region of NF-κB p50.
- Bisdemethoxycurcumin induced autophagy, reduced senescence markers, and lowered Aβ load in 3xTg-AD mice hippocampus.
Frequently asked questions
What is Hidden-Lily?
Hidden-Lily (Curcuma) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Hidden-Lily?
8 sourced findings are recorded for Hidden-Lily; the strongest carries evidence grade A. For example: The study found that Astragalus-Curcuma zedoaria combination modulates gene expression and targets vascular endothelial cells via demethoxycurcumin.
How strong is the evidence for Hidden-Lily?
The strongest finding for Hidden-Lily carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Hidden-Lily safe? What are the side effects?
No major safety issues are recorded for Hidden-Lily in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Hidden-Lily interact with medications?
No drug interactions are recorded for Hidden-Lily in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Hidden-Lily?
Hidden-Lily is also known as: Куркума, Curcumas.
Is Hidden-Lily a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Curcumin versus placebo in benign prostatic hyperplasia: a systematic review and meta-analysis. literature abstract metadata
- T2 Local curcumin/turmeric-derived delivery adjunctive to scaling and root planing for periodontitis: a systematic review and meta-analysis. literature abstract metadata
- T2 Integrating Seropharmacology, Network Pharmacology, and Single-Cell Transcriptomics to Decipher the Dual Anti-Tumor Mechanisms of Astragalus-Curcuma zedoaria in Lung Squamous Cell Carcinoma. literature abstract metadata
- T2 AMPK-mediated autophagy induction by bisdemethoxycurcumin attenuates senescence and amyloid pathology in 3xTg-AD mice. literature abstract metadata
- T2 Molecular dynamics and free energy analysis of curcumin binding near the DNA-recognition interface of NF-κB. literature abstract metadata
- T2 Curcumin Metabolites and Metabolic Health: Insights into Regulatory Mechanisms of Glucose and Lipid Homeostasis. literature abstract metadata
- T2 Integrated network pharmacology reveal new key curcumin-binding targets in triple-negative breast cancer. literature abstract metadata
- T2 Exploring the Potential of Calebin-A in Targeting Obesity-Related Genes and Pathways. literature abstract metadata