Japanese gentian
Gentiana scabra
Gentiana scabra is a traditional Chinese medicinal plant. It has been used in various practices, particularly within Traditional Chinese Medicine (TCM), for its purported health benefits. Scientific studies have shown that Gentiana scabra exhibits potential therapeutic effects, including modulation of immune responses and reduction of blood pressure. For instance, GPS treatment derived from this plant was found to alleviate psoriasis-like skin lesions by modulating immune homeostasis and suppressing NF-κB activation in mice. Additionally, it has been observed to lower blood pressure in rats with chronic stress-induced hypertension through the modulation of multiple signaling pathways. Gentiana scabra extract also showed varying efficacy against Eimeria tenella-induced coccidiosis in broilers, with a 2 g/kg dose achieving optimal results by improving gut health and modulating the microbiota-metabolome. To date, no major safety issues or drug interactions have been recorded for this plant, but further research is needed to fully understand its potential applications and mechanisms of action.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Metabolic differences and gene expression variations were identified among Gentiana scabra grown in wild shrublands, wild meadows, and cultivated farmlands.
- GPS treatment significantly alleviated psoriasis-like skin lesions in mice by modulating immune homeostasis and suppressing NF-κB activation.
- The study found that Longdan Xiegan Pills may lower blood pressure in chronic stress-induced hypertension rats through multiple signaling pathways.
- Gentiana scabra extract showed varying efficacy against Eimeria tenella-induced coccidiosis in broilers, with optimal results at 2 g/kg dose.
Frequently asked questions
What is Japanese gentian?
Japanese gentian (Gentiana scabra) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Japanese gentian?
4 sourced findings are recorded for Japanese gentian; the strongest carries evidence grade D. For example: Metabolic differences and gene expression variations were identified among Gentiana scabra grown in wild shrublands, wild meadows, and cultivated farmlands.
How strong is the evidence for Japanese gentian?
The strongest finding for Japanese gentian carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Japanese gentian safe? What are the side effects?
No major safety issues are recorded for Japanese gentian in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Japanese gentian interact with medications?
No drug interactions are recorded for Japanese gentian in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Japanese gentian?
Japanese gentian is also known as: Горечавка шероховатая, Gentiane japonaise.
Is Japanese gentian a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Gentiana scabra mitigates Eimeria tenella-induced Coccidiosis by regulating the gut microbiota-metabolome and strengthening the intestinal barrier. literature abstract metadata
- T2 The mechanism of Longdan Xiegan pills in chronic stress-induced hypertension:a study based on network pharmacology and experimentalvalidation. literature abstract metadata
- T2 Gentiopicroside Ameliorates Psoriasis-Like Dermatitis by Modulating Immune Homeostasis and Suppressing NF-κB Activation. literature abstract metadata
- T2 Metabolome and transcriptome analyses reveal metabolic differences and identify candidate regulatory factors among three habitat types of Gentiana scabra Bunge. literature abstract metadata