Japanese gentian
Gentiana scabra
Gentiana scabra is a traditional Chinese herb used primarily for its purported medicinal properties. While specific traditional uses are not well-documented, it has been employed in various East Asian medical practices. Scientific evidence suggests that Gentiana scabra exhibits varying levels of efficacy; metabolic differences and gene expression variations have been noted among plants grown in different environments. Research indicates that GPS treatment derived from Gentiana scabra may alleviate psoriasis-like skin lesions by modulating immune homeostasis and suppressing NF-κB activation, and it has shown potential in lowering blood pressure in rats with chronic stress-induced hypertension through multiple signaling pathways. Additionally, extracts of the plant have demonstrated varying effectiveness against Eimeria tenella-induced coccidiosis in broilers, with optimal results observed at a 2 g/kg dose. Safety concerns are minimal, as no major issues or drug interactions have been recorded to date.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Metabolic differences and gene expression variations were identified among Gentiana scabra grown in wild shrublands, wild meadows, and cultivated farmlands.
- GPS treatment significantly alleviated psoriasis-like skin lesions in mice by modulating immune homeostasis and suppressing NF-κB activation.
- The study found that Longdan Xiegan Pills may lower blood pressure in chronic stress-induced hypertension rats through multiple signaling pathways.
- Gentiana scabra extract showed varying efficacy against Eimeria tenella-induced coccidiosis in broilers, with optimal results at 2 g/kg dose.
Frequently asked questions
What is Japanese gentian?
Japanese gentian (Gentiana scabra) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Japanese gentian?
4 sourced findings are recorded for Japanese gentian; the strongest carries evidence grade D. For example: Metabolic differences and gene expression variations were identified among Gentiana scabra grown in wild shrublands, wild meadows, and cultivated farmlands.
How strong is the evidence for Japanese gentian?
The strongest finding for Japanese gentian carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Japanese gentian safe? What are the side effects?
No major safety issues are recorded for Japanese gentian in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Japanese gentian interact with medications?
No drug interactions are recorded for Japanese gentian in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Japanese gentian?
Japanese gentian is also known as: Горечавка шероховатая, Gentiane japonaise.
Is Japanese gentian a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Gentiana scabra mitigates Eimeria tenella-induced Coccidiosis by regulating the gut microbiota-metabolome and strengthening the intestinal barrier. literature abstract metadata
- T2 The mechanism of Longdan Xiegan pills in chronic stress-induced hypertension:a study based on network pharmacology and experimentalvalidation. literature abstract metadata
- T2 Gentiopicroside Ameliorates Psoriasis-Like Dermatitis by Modulating Immune Homeostasis and Suppressing NF-κB Activation. literature abstract metadata
- T2 Metabolome and transcriptome analyses reveal metabolic differences and identify candidate regulatory factors among three habitat types of Gentiana scabra Bunge. literature abstract metadata