Sophora alopecuroides
Sophora alopecuroides
Sophora alopecuroides，又称黄柏或中国决明子根，在东亚草药实践中被用作传统药材。它因其被认为具有抗炎和抗菌作用而被传统上使用，尽管具体的用途可能因不同的传统而异且缺乏明确的记录。 科学研究表明，从 Sophora alopecuroides 中提取的化合物表现出显著的抗炎效果，通过抑制一氧化氮（NO）、肿瘤坏死因子-α（TNF-α）和白细胞介素-6（IL-6）的产生。此外，它还显示出减轻肺缺血再灌注损伤的潜力，通过 STAT-1 途径调节铁死亡。研究表明其具有抗肿瘤作用，特别是对卵巢癌通过调节三羧酸循环和糖酵解以及对抗乳腺癌中的多药耐药性；然而，进一步的研究是必要的以确定特定活性成分及其机制。 尚未记录 Sophora alopecuroides 的重大安全问题。也没有报告与其使用相关的药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 来自 Sophora alopecuroides 的 ALOperine 展现出对卵巢癌的抑制作用，通过调节三羧酸循环和糖酵解。
- 来自 Sophora alopecuroides 的两种新的马特林甲基化衍生物通过抑制 NO、TNF-α 和 IL-6 的产生以及下调 iNOS 和 COX-2 来表现出强大的抗炎作用。
- 阿洛佩金通过STAT-1途径调节铁死亡减轻了肺缺血再灌注损伤，但没有提供明确的健康建议。
- 来自 Sophora alopecuroides 的氯仿提取物在对抗乳腺癌多药耐药性方面显示出潜力，尽管具体的活性成分和作用机制仍需进一步研究。
Frequently asked questions
What is Sophora alopecuroides?
Sophora alopecuroides (Sophora alopecuroides) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Sophora alopecuroides?
4 sourced findings are recorded for Sophora alopecuroides; the strongest carries evidence grade D. For example: 来自 Sophora alopecuroides 的 ALOperine 展现出对卵巢癌的抑制作用，通过调节三羧酸循环和糖酵解。
How strong is the evidence for Sophora alopecuroides?
The strongest finding for Sophora alopecuroides carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Sophora alopecuroides safe? What are the side effects?
No major safety issues are recorded for Sophora alopecuroides in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Sophora alopecuroides interact with medications?
No drug interactions are recorded for Sophora alopecuroides in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Sophora alopecuroides?
Sophora alopecuroides is also known as: Софора лисохвостная.
Is Sophora alopecuroides a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Computational and Experimental Analysis of Sophora alopecuroides L. Chloroform Fraction: Active Components and Anti-Breast Cancer Resistance Mechanisms. literature abstract metadata
- T2 Aloperine exerts anti-ovarian cancer effects by regulating the tricarboxylic acid cycle and glycolysis: A comprehensive study integrating network pharmacology, molecular docking, metabolomics, and experimental validation. literature abstract metadata
- T2 Aloperine alleviates lung ischemia-reperfusion injury by modulating ferroptosis via the STAT-1 pathway. literature abstract metadata
- T2 Two new matrine-methyl adducts from Sophora alopecuriodes with anti-inflammatory activity via ROS/HIF-1α regulation. literature abstract metadata