Sophora exigua

Sophora exigua

Sophora exigua,一种传统的中国药用植物,在其传统中没有广泛记录特定用途。科学研究表明,从 Sophora exigua 提取的提取物表现出抗炎、抗增殖和抗转移作用于肺癌细胞通过 NLRP3 炎症小体抑制。根部的乙醇提取物还显示出抗氧化性质,而水提取物在小鼠中显示了抗疟疾活性。这表明从农业食品副产品中开发生物农药的潜在生物活性化合物。Sophoraflavanone G 被发现可以抑制 WT1 蛋白表达并诱导急性髓系白血病细胞周期停滞和凋亡。尚未记录主要的安全问题或药物相互作用,但需要进一步研究以全面了解其潜在益处和应用。

速览
最佳证据
A
注意事项

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同,请查阅所引来源。

科学怎么说

  • Sophora exigua 提取物及其活性化合物 exiguaflavanone A 和 exiguaflavanone B 在抑制 NLRP3 炎症小体的情况下,对肺癌细胞显示出抗炎、抗增殖和抗转移作用。 D PMID
  • 桑叶根乙醇提取物显示出抗氧化作用,而水提取物在小鼠中表现出抗疟疾活性。 D PMID
  • 这项系统性回顾表明,橄榄、马铃薯、香蕉、柑橘和酿酒工业等食品加工业的副产品可能成为生物农药开发中潜在的活性化合物来源。 A PMID
  • 从苦豆子中提取的Sophorafavanone G抑制WT1蛋白表达并诱导急性髓系白血病细胞周期停滞和凋亡。 D PMID
  • 桑叶乙酸萃取物显示出强烈的抗氧化活性,其脂质体制剂保持了这一特性。 D PMID

Frequently asked questions

What is Sophora exigua?

Sophora exigua (Sophora exigua) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Sophora exigua?

5 sourced findings are recorded for Sophora exigua; the strongest carries evidence grade A. For example: Sophora exigua 提取物及其活性化合物 exiguaflavanone A 和 exiguaflavanone B 在抑制 NLRP3 炎症小体的情况下,对肺癌细胞显示出抗炎、抗增殖和抗转移作用。

How strong is the evidence for Sophora exigua?

The strongest finding for Sophora exigua carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).

Is Sophora exigua safe? What are the side effects?

No major safety issues are recorded for Sophora exigua in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Sophora exigua interact with medications?

No drug interactions are recorded for Sophora exigua in our sources. This does not rule them out — check with a pharmacist.

Is Sophora exigua a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Antioxidant and antimalarial properties of Sophora exigua Craib. root extract in Plasmodium berghei-infected mice. literature abstract metadata
  2. T2 Suppression of inflammation-induced lung cancer cells proliferation and metastasis by exiguaflavanone A and exiguaflavanone B from Sophora exigua root extract through NLRP3 inflammasome pathway inhibition. literature abstract metadata
  3. T2 Antioxidant activity of Sophora exigua and liposome development of its powerful extract. literature abstract metadata
  4. T2 Sophoraflavanone G from Phit-Sanat (Sophora Exigua Craib) inhibits WT1 protein expression and induces cell cycle arrest and apoptosis in acute myeloid leukemia. literature abstract metadata
  5. T2 Agri-Food Biowaste Bioactives for Biopesticides: A Circular Economy Solution with Industry 4.0? literature abstract metadata