Sophora alopecuroides
Sophora alopecuroides
Sophora alopecuroides is a traditional Chinese medicinal plant. It has been used in various folk remedies, though specific traditional uses are not well-documented. Scientific evidence suggests that ALOperine from this plant may have anti-ovarian cancer effects and modulate the tricarboxylic acid cycle and glycolysis. Additionally, two new matrine-methyl adducts show potent anti-inflammatory properties by inhibiting NO, TNF-α, and IL-6 production. Aloperine also alleviates lung ischemia-reperfusion injury through modulation of the STAT-1 pathway. The chloroform fraction exhibits potential in countering multidrug resistance in breast cancer, though further investigation is needed to identify specific active components and mechanisms. No major safety issues or recorded drug interactions have been noted for Sophora alopecuroides.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- ALOperine from Sophora alopecuroides exhibits anti-ovarian cancer effects by modulating the tricarboxylic acid cycle and glycolysis.
- Two new matrine-methyl adducts from Sophora alopecuroides show potent anti-inflammatory properties by inhibiting NO, TNF-α, and IL-6 production and down-regulating iNOS and COX-2.
- Aloperine alleviated lung ischemia-reperfusion injury by modulating ferroptosis via the STAT-1 pathway, but no definitive health advice is provided.
- The chloroform fraction from Sophora alopecuroides exhibited potential in counteracting multidrug resistance in breast cancer, though specific active components and mechanisms require further investigation.
Frequently asked questions
What is Sophora alopecuroides?
Sophora alopecuroides (Sophora alopecuroides) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Sophora alopecuroides?
4 sourced findings are recorded for Sophora alopecuroides; the strongest carries evidence grade D. For example: ALOperine from Sophora alopecuroides exhibits anti-ovarian cancer effects by modulating the tricarboxylic acid cycle and glycolysis.
How strong is the evidence for Sophora alopecuroides?
The strongest finding for Sophora alopecuroides carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Sophora alopecuroides safe? What are the side effects?
No major safety issues are recorded for Sophora alopecuroides in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Sophora alopecuroides interact with medications?
No drug interactions are recorded for Sophora alopecuroides in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Sophora alopecuroides?
Sophora alopecuroides is also known as: Софора лисохвостная.
Is Sophora alopecuroides a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Computational and Experimental Analysis of Sophora alopecuroides L. Chloroform Fraction: Active Components and Anti-Breast Cancer Resistance Mechanisms. literature abstract metadata
- T2 Aloperine exerts anti-ovarian cancer effects by regulating the tricarboxylic acid cycle and glycolysis: A comprehensive study integrating network pharmacology, molecular docking, metabolomics, and experimental validation. literature abstract metadata
- T2 Aloperine alleviates lung ischemia-reperfusion injury by modulating ferroptosis via the STAT-1 pathway. literature abstract metadata
- T2 Two new matrine-methyl adducts from Sophora alopecuriodes with anti-inflammatory activity via ROS/HIF-1α regulation. literature abstract metadata