Stephania venosa
Stephania venosa
Stephania venosa is a climbing plant utilized within various traditional medicinal practices. It is traditionally applied to address cough, physical weakness, and various skin diseases. Preliminary scientific research suggests that certain compounds from the plant, such as crebanine, may inhibit the proliferation of renal and hepatocellular carcinoma cells in laboratory settings. Additionally, some components appear to suppress inflammatory responses in macrophage models and may enhance the sensitivity of certain ovarian cancer cells to cisplatin. No major safety issues or notable drug interactions have been recorded in available data. This information is for educational purposes only.
- Traditionally for
- cough · weakness
- Traditions
- Thai traditional
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
Traditional use
- cough
- weakness
- skin diseases
What the science says
- Crebanine significantly inhibited renal cell carcinoma colonies and induced G1-phase arrest with sub-G1 accumulation, leading to suppressed proliferation and apoptosis.
- Crebanine from Stephania venosa suppresses hepatocellular carcinoma proliferation and invasion by modulating the EZH2/DUSP1/Akt signaling pathway.
- OMP and DC suppressed LPS-induced inflammatory response in RAW264.7 macrophages by inhibiting NF-κB and AP-1 activation.
- CN and OMBC enhance cisplatin sensitivity in SKOV3 ovarian cancer cells by inhibiting Akt/NF-κB signaling.
Frequently asked questions
What is Stephania venosa?
Stephania venosa (Stephania venosa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What is Stephania venosa traditionally used for?
Traditional sources record Stephania venosa for: cough, weakness, skin diseases. This reflects traditional use, not a proven medical treatment.
Which traditions use Stephania venosa?
Stephania venosa appears in these traditions in our sources: Thai traditional.
What does the scientific evidence say about Stephania venosa?
4 sourced findings are recorded for Stephania venosa; the strongest carries evidence grade D. For example: Crebanine significantly inhibited renal cell carcinoma colonies and induced G1-phase arrest with sub-G1 accumulation, leading to suppressed proliferation and apoptosis.
How strong is the evidence for Stephania venosa?
The strongest finding for Stephania venosa carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Stephania venosa safe? What are the side effects?
No major safety issues are recorded for Stephania venosa in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Stephania venosa interact with medications?
No drug interactions are recorded for Stephania venosa in our sources. This does not rule them out — check with a pharmacist.
Is Stephania venosa a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Alkaloids from Stephania venosa as Chemo-Sensitizers in SKOV3 Ovarian Cancer Cells via Akt/NF-κB Signaling. literature abstract metadata
- T2 O-Methylbulbocapnine and Dicentrine Suppress LPS-Induced Inflammatory Response by Blocking NF-κB and AP-1 Activation through Inhibiting MAPKs and Akt Signaling in RAW264.7 Macrophages. literature abstract metadata
- T2 Crebanine Induces Cell Death and Alters the Mitotic Process in Renal Cell Carcinoma In Vitro. literature abstract metadata
- T2 EZH2/DUSP1/Akt signaling axis mediates the inhibitory effect of crebanine on hepatocellular carcinoma progression. literature abstract metadata
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