FolkKB

candyleaf

Stevia rebaudiana

Stevia rebaudiana 是一种原产于南美洲的植物，因其甜味剂特性而被广泛使用。传统上，它在已知的任何传统中都未与具体药用用途相关联。科学证据表明，stevioside 可能通过激活 ATFS-1 调控的 UPRmt 通路延长线虫的寿命并改善健康状况，但这一发现目前仅限于动物模型。拉曼光谱可区分天然来源、发酵产生以及酶促生物转化的 Rebaudioside M 源，这可能对质量控制具有影响。此外，Stevia 提取物已显示出在小鼠中通过抑制 TLR4/MYD88/NF-κB 信号通路部分缓解 LPS‑诱导的脾脏炎症损伤，提示其潜在抗炎作用。UGT76G 基因簇被认为是导致甜味素组成和口感质量差异的重要因素。目前未记录该植物存在重大安全问题或药物相互作用。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 在C. elegans中，甜菊苷通过激活ATFS-1介导的UPRmt途径延长寿命和健康跨度。 D PMID
  • 拉曼光谱可以区分天然存在的、发酵衍生的和酶辅助生物转化的Rebaudioside M来源。 D PMID
  • 研究发现与甜菊糖苷组成变异相关的UGT76G基因簇，有助于口味质量的差异。 D PMID
  • 从鼠李糖柳涵提取物部分缓解了由LPS诱导的小鼠脾脏炎症损伤，通过抑制TLR4/MYD88/NF-κB信号通路。 D PMID
  • 研究生成了详细的植物化学特征图谱，对Stevia rebaudiana进行了鉴定，并确定了14种化合物和8种主要代谢物的含量。 D PMID

Frequently asked questions

What is candyleaf?

candyleaf (Stevia rebaudiana) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about candyleaf?

5 sourced findings are recorded for candyleaf; the strongest carries evidence grade D. For example: 在C. elegans中，甜菊苷通过激活ATFS-1介导的UPRmt途径延长寿命和健康跨度。

How strong is the evidence for candyleaf?

The strongest finding for candyleaf carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is candyleaf safe? What are the side effects?

No major safety issues are recorded for candyleaf in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does candyleaf interact with medications?

No drug interactions are recorded for candyleaf in our sources. This does not rule them out — check with a pharmacist.

What are the common names of candyleaf?

candyleaf is also known as: Стевия медовая, stévia.

Is candyleaf a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Feature-Based Molecular Networking Approach for Exploring the Chemical Profile and Quantification of Polyphenols in Stevia rebaudiana, Bertoni Using HR-LC-ESI-Orbitrap-MSn. literature abstract metadata
  2. T2 Multi-omics dissection of steviol glycoside synthesis reveals haplotype-linked specialization of UGT76G genes in Stevia rebaudiana. literature abstract metadata
  3. T2 Stevioside extends the healthspan and improves Alzheimer's disease and increases oxidative stress resistance via the mitochondrial unfolded protein response. literature abstract metadata
  4. T2 Stevia extract alleviated spleen inflammatory injury in LPS-stressed mice by inhibiting the TLR4/MYD88/NF-κB signaling pathway. literature abstract metadata
  5. T2 Raman Spectroscopic Authentication of Rebaudioside M: Discriminating Natural, Fermentation-Derived, and Enzymatically Bioconverted Stevia Sweeteners. literature abstract metadata