FolkKB

Big Leaf Mahogany

Swietenia macrophylla

Swietenia macrophylla，又称大叶桃花心木，是一种原产于中美洲和南美洲的传统草药植物。尽管其在特定传统实践中的使用尚未广泛记录，但研究表明结果令人鼓舞。科学研究表明，来自Swietenia macrophylla的swietenine可以改善糖尿病肾病大鼠的肾脏功能并减少纤维化，通过增强自噬作用。此外，从该植物中分离出的limonoid swietenolide在体外和计算机模拟研究中均显示出作为α-葡萄糖苷酶抑制剂的潜力，这可能有助于管理血糖水平。该研究还强调了使用紧凑型质谱仪进行玻璃化冷冻保存以100%准确度识别Swietenia macrophylla的应用。迄今为止尚未发现重大安全问题或药物相互作用。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • Swietenine改善了糖尿病肾病大鼠的肾脏功能并减少了纤维化，通过增强自噬作用。 D PMID
  • 这项研究展示了使用紧凑型质谱仪对四种热带硬木物种进行识别时达到100%的分类准确性，其中包括Swietenia macrophylla。 D PMID
  • 该研究描述了使用玻璃化冷冻保存Swietenia macrophylla的方法，但具体的成果在此未作详细说明。 D PMID
  • 从Swietenia macrophylla中分离出的limonoid swietenolide在体外和计算机模拟研究中显示出作为α-葡萄糖苷酶抑制剂的潜力。 D PMID

Frequently asked questions

What is Big Leaf Mahogany?

Big Leaf Mahogany (Swietenia macrophylla) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Big Leaf Mahogany?

4 sourced findings are recorded for Big Leaf Mahogany; the strongest carries evidence grade D. For example: Swietenine改善了糖尿病肾病大鼠的肾脏功能并减少了纤维化，通过增强自噬作用。

How strong is the evidence for Big Leaf Mahogany?

The strongest finding for Big Leaf Mahogany carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Big Leaf Mahogany safe? What are the side effects?

No major safety issues are recorded for Big Leaf Mahogany in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Big Leaf Mahogany interact with medications?

No drug interactions are recorded for Big Leaf Mahogany in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Big Leaf Mahogany?

Big Leaf Mahogany is also known as: Acajou.

Is Big Leaf Mahogany a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Real-Time Wood Chemotyping Using a Low-Cost and Compact Mass Spectrometer. literature abstract metadata
  2. T2 In silico and in vitro study for the limonoid isolated from Swietenia macrophylla as potential α-glucosidase inhibitor. literature abstract metadata
  3. T2 Long-Term Preservation by Cryopreservation Method Swietenia macrophylla King. literature abstract metadata
  4. T2 Swietenine Enhances Autophagy to Improve Renal Fibrosis via AMPK/mTOR/ULK1 Signaling Pathway in Diabetic Nephropathy. literature abstract metadata