Acajou
Swietenia macrophylla · Big Leaf Mahogany
Swietenia macrophylla, commonly known as bigleaf mahogany, is a tropical hardwood native to Central America and parts of South America. While its traditional medicinal uses are not well-documented in historical or cultural practices, scientific research has shown some promise. Studies indicate that swietenine from Swietenia macrophylla improved renal function and reduced fibrosis in diabetic nephropathy rats by enhancing autophagy. Additionally, atmospheric solids analysis probe mass spectrometry accurately classified this species with 100% accuracy, highlighting its potential for identification and authentication. In vitro and in silico studies suggest that the isolated limonoid swietenolide may have potential as an α-glucosidase inhibitor, though specific outcomes are not detailed here. Safety concerns do not appear to be significant based on current data, and there are no recorded drug interactions associated with Swietenia macrophylla.
- Meilleure preuve
- D
- Précautions
- —
Information uniquement. L'usage traditionnel ne signifie pas une efficacité prouvée. Les preuves et la sécurité varient — consultez les sources citées.
Ce que dit la science
- La swietenine a amélioré la fonction rénale et réduit la fibrose chez les rats de néphropathie diabétique en augmentant l'autophagie.
- Cette étude montre une précision de classification à 100 % en utilisant un spectromètre de masse compact pour identifier quatre espèces de bois tropicaux, y compris Swietenia macrophylla.
- L'étude décrit l'application de la cryopreservation par vitrification pour Swietenia macrophylla, bien que les résultats spécifiques ne soient pas détaillés ici.
- Le limonoid isolé swietenolide de Swietenia macrophylla a montré un potentiel d'inhibiteur de l'α-glucosidase par des études in vitro et in silico.
Frequently asked questions
What is Acajou?
Acajou (Swietenia macrophylla) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Acajou?
4 sourced findings are recorded for Acajou; the strongest carries evidence grade D. For example: La swietenine a amélioré la fonction rénale et réduit la fibrose chez les rats de néphropathie diabétique en augmentant l'autophagie.
How strong is the evidence for Acajou?
The strongest finding for Acajou carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Acajou safe? What are the side effects?
No major safety issues are recorded for Acajou in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Acajou interact with medications?
No drug interactions are recorded for Acajou in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Acajou?
Acajou is also known as: Big Leaf Mahogany.
Is Acajou a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Real-Time Wood Chemotyping Using a Low-Cost and Compact Mass Spectrometer. literature abstract metadata
- T2 In silico and in vitro study for the limonoid isolated from Swietenia macrophylla as potential α-glucosidase inhibitor. literature abstract metadata
- T2 Long-Term Preservation by Cryopreservation Method Swietenia macrophylla King. literature abstract metadata
- T2 Swietenine Enhances Autophagy to Improve Renal Fibrosis via AMPK/mTOR/ULK1 Signaling Pathway in Diabetic Nephropathy. literature abstract metadata