Celebes papeda
Citrus hystrix
Citrus hystrix, also known as kaffir lime, is a traditional plant used in Southeast Asian and other regional cuisines. While its use in traditional medicine has not been extensively documented, studies have shown that extracts from its peel exhibit varying bioactivities. Hexane and essential oil extracts demonstrated stronger 5α-reductase inhibition, whereas ethanolic extracts were more effective against inflammatory targets. A systematic review indicated that Citrus hystrix significantly reduced nitric oxide (NO) production and levels of tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6) in both in vitro and in vivo models, suggesting potential anti-inflammatory properties. The study also found that the type of citrus fruit influenced the volatile organic compound profiles in flavored sesame, palm, and coconut oils. No major safety issues or drug interactions have been recorded for Citrus hystrix to date.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Citrus hystrix peel extracts showed varying bioactivities with hexane and essential oil extracts exhibiting stronger 5α-reductase inhibition while ethanolic extract more effectively inhibited inflammatory targets.
- The study found that the type of citrus fruit significantly influenced the volatile organic compound profiles in flavored sesame, palm, and coconut oils.
- The systematic review found that Citrus hystrix significantly reduced NO production, TNF-α, and IL-6 levels in both in vitro and in vivo models.
- The study assembled both subgenomes of Mexican lime (Citrus × aurantifolia), revealing extensive haplotype divergence while maintaining syntenic gene pairs.
Frequently asked questions
What is Celebes papeda?
Celebes papeda (Citrus hystrix) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Celebes papeda?
4 sourced findings are recorded for Celebes papeda; the strongest carries evidence grade D. For example: Citrus hystrix peel extracts showed varying bioactivities with hexane and essential oil extracts exhibiting stronger 5α-reductase inhibition while ethanolic extract more effectively inhibited inflammatory targets.
How strong is the evidence for Celebes papeda?
The strongest finding for Celebes papeda carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Celebes papeda safe? What are the side effects?
No major safety issues are recorded for Celebes papeda in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Celebes papeda interact with medications?
No drug interactions are recorded for Celebes papeda in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Celebes papeda?
Celebes papeda is also known as: Кафир-лайм, Combava.
Is Celebes papeda a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Diploid assembly of the Mexican lime genome. literature abstract metadata
- T2 Characterization of Volatile Organic Compounds in Citrus-Flavored Sesame, Palm, and Coconut Oils Using Gas Chromatography-Mass Spectrometry and Multivariate Analysis. literature abstract metadata
- T2 Differential Anti-Acne Activities of Citrus hystrix Peel Extracts: 5α-Reductase Inhibition, Anti-Inflammatory, and Antimicrobial Effects. literature abstract metadata
- T2 The anti-inflammatory effects of Citrus hystrix DC.: a systematic review and meta-analysis of in vitro and in vivo studies. literature abstract metadata