Celebes papeda

Citrus hystrix, commonly known as kaffir lime, is a traditional plant used primarily for culinary purposes. While its use in traditional medicine has not been extensively documented, studies have shown that extracts from its peel exhibit varying bioactivities, with hexane and essential oil extracts demonstrating stronger 5α-reductase inhibition compared to ethanolic extracts, which more effectively inhibited inflammatory targets. The bioactivity findings are promising but require further investigation as the evidence is still limited in scope. Notably, the type of citrus fruit significantly influenced the volatile organic compound profiles found in flavored sesame, palm, and coconut oils. Additionally, a systematic review and meta-analysis indicated that Citrus hystrix may reduce nitric oxide production, tumor necrosis factor-α (TNF-α), and interleukin-6 (IL-6) levels both in vitro and in vivo models, though the strength of these findings is currently moderate due to limited studies. No major safety concerns or drug interactions have been recorded for Citrus hystrix, but further research is needed to fully understand its potential benefits and applications.

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.