Brindal Berry
Garcinia cowa
Garcinia cowa is a plant traditionally found in Southeast Asia. While it has not been extensively used in traditional medicine, studies have shown promise for its potential applications. Scientific evidence indicates that phytochemicals from Garcinia cowa may interact with SASP2-DNA and inhibit breast cancer cell growth, migration, and metastasis both in vitro and in vivo. Additionally, a chamuangone-enriched extract demonstrated antibacterial activity against MRSA. The taxonomy of the species has been revised, consolidating four taxa under G. cowa var. cowa and two under G. oliveri. Safety concerns for Garcinia cowa are currently minimal, with no major issues recorded. There is also no reported evidence of drug interactions at this time.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Several phytochemicals from Garcinia cowa showed potential to interact with the SASP2-DNA interface, potentially affecting spore viability.
- The taxonomy of Garcinia cowa, G. oliveri, and G. schomburgkiana is revised, with four taxa synonymized under G. cowa var. cowa and two under G. oliveri.
- A chamuangone-enriched extract from Garcinia cowa significantly inhibited breast cancer lung metastasis in both in vitro and in vivo studies.
- Two butenolide derivatives were isolated from Aspergillus terreus GCD2 associated with Garcinia cowa, and one exhibited notable antibacterial activity against MRSA.
Frequently asked questions
What is Brindal Berry?
Brindal Berry (Garcinia cowa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Brindal Berry?
4 sourced findings are recorded for Brindal Berry; the strongest carries evidence grade D. For example: Several phytochemicals from Garcinia cowa showed potential to interact with the SASP2-DNA interface, potentially affecting spore viability.
How strong is the evidence for Brindal Berry?
The strongest finding for Brindal Berry carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Brindal Berry safe? What are the side effects?
No major safety issues are recorded for Brindal Berry in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Brindal Berry interact with medications?
No drug interactions are recorded for Brindal Berry in our sources. This does not rule them out — check with a pharmacist.
Is Brindal Berry a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Antimetastatic effects of chamuangone-enriched extract in breast cancer lung metastasis: in vitro and in vivo evidence. literature abstract metadata
- T2 Taxonomic treatment of three Garcinia species (section Brindonia, Clusiaceae) in Thailand, with six new synonyms and ten lectotypifications. literature abstract metadata
- T2 Isolation of butenolide compounds from endophytic Aspergillus terreus GDC2 associated with Garcinia cowa and their anti-MRSA activity: in vitro and in silico insights. literature abstract metadata
- T2 Phytochemical targeting of SASP2-mediated DNA protection to impair spore resilience in Bacillus cereus: A Computational Investigation. literature abstract metadata