Goa-butter
Garcinia indica
Garcinia indica, also known as kokum, is a traditional plant primarily used in Indian and Sri Lankan cuisines. While its use in traditional medicine is not well-documented, studies suggest potential benefits such as improving memory functions and neuroprotection through the inhibition of HAT enzymes. Additionally, Garcinol from Garcinia indica has shown promise in mitigating Alzheimer's-like symptoms by regulating oxidative stress, acetylcholinesterase (AChE) activity, and pro-inflammatory cytokines in Drosophila melanogaster models. Moreover, there is evidence that Garcinol may have anti-cancer properties as an epigenetic modulator; however, more human studies are needed to confirm these findings. In terms of safety, no major issues have been recorded, and there are currently no known drug interactions associated with Garcinia indica.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study suggests that Garcinol from Garcinia indica may potentially improve memory functions and neuroprotection by inhibiting HAT enzymes.
- Garcinol from Garcinia indica showed potential in mitigating Alzheimer's-like neurodegeneration in Drosophila melanogaster by regulating oxidative stress, AChE activity, and pro-inflammatory cytokines.
- Garcinol, derived from Garcinia indica, shows potential as an epigenetic modulator with anti-cancer activities, but further human studies are needed.
- Combined supplementation with astaxanthin and kokum modulated redox status and lysosomal degradation in a murine model of diet-induced NAFLD.
Frequently asked questions
What is Goa-butter?
Goa-butter (Garcinia indica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Goa-butter?
4 sourced findings are recorded for Goa-butter; the strongest carries evidence grade D. For example: The study suggests that Garcinol from Garcinia indica may potentially improve memory functions and neuroprotection by inhibiting HAT enzymes.
How strong is the evidence for Goa-butter?
The strongest finding for Goa-butter carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Goa-butter safe? What are the side effects?
No major safety issues are recorded for Goa-butter in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Goa-butter interact with medications?
No drug interactions are recorded for Goa-butter in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Goa-butter?
Goa-butter is also known as: гарциния индийская.
Is Goa-butter a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Garcinol as an Epigenetic Modulator: Mechanisms of Anti-Cancer Activity and Therapeutic Potential. literature abstract metadata
- T2 Antioxidant Intervention in NAFLD: Astaxanthin and Kokum Modulate Redox Status and Lysosomal Degradation. literature abstract metadata
- T2 Protective effects of the natural polyphenol garcinol from Garcinia indica mitigates aluminium chloride-induced Alzheimer's-like neurodegeneration in Drosophila melanogaster. literature abstract metadata
- T2 Epigenetic Modulation Is a Key Mechanism in Cognitive Deficit: Unveiling Garcinol as a Potent HAT Inhibitor in Improving Alzheimer's Disease. literature abstract metadata