Garcinia morella
Garcinia morella
Garcinia morella, also known as Indian Garcinia or Kalmegh, is traditionally used in Ayurvedic medicine for various conditions but specific uses are not well-documented. Scientific evidence suggests that extracts from this plant may provide dopaminergic neuroprotection and mitigate mitochondrial dysfunctions and inflammation in mouse models of Parkinson's disease. Additionally, it has shown antioxidant, antifungal, and anti-inflammatory properties, with a fraction enriched in Garcinol demonstrating potential benefits for liver function and gut health in mice on a high-fat diet. Gambogic acid from this plant also exhibited favorable safety profiles in clinical studies. No significant safety concerns or drug interactions have been reported to date.
- Best evidence
- B
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study found that gambogic acid had a favorable safety profile and showed higher disease control rates in patients receiving it from Day 1 to 5 of a 2-week cycle compared to every other day.
- Garcinia morella extract provided dopaminergic neuroprotection in a mouse model of Parkinson's disease by mitigating mitochondrial dysfunctions and inflammation.
- Garcinia morella exhibits various biological activities including antioxidant, antifungal, and anti-inflammatory properties, among others.
- Garcinol-enriched fraction from Garcinia morella fruit rind reduced liver dysfunction markers and improved gut health in high-fat diet-fed mice.
Frequently asked questions
What is Garcinia morella?
Garcinia morella (Garcinia morella) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Garcinia morella?
4 sourced findings are recorded for Garcinia morella; the strongest carries evidence grade B. For example: The study found that gambogic acid had a favorable safety profile and showed higher disease control rates in patients receiving it from Day 1 to 5 of a 2-week cycle compared to every other day.
How strong is the evidence for Garcinia morella?
The strongest finding for Garcinia morella carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Garcinia morella safe? What are the side effects?
No major safety issues are recorded for Garcinia morella in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Garcinia morella interact with medications?
No drug interactions are recorded for Garcinia morella in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Garcinia morella?
Garcinia morella is also known as: Гарциния морелла.
Is Garcinia morella a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 An open-labeled, randomized, multicenter phase IIa study of gambogic acid injection for advanced malignant tumors. literature abstract metadata
- T2 Phytochemicals and Biological Activities of Garcinia morella (Gaertn.) Desr.: A Review. literature abstract metadata
- T2 Garcinia morella extract confers dopaminergic neuroprotection by mitigating mitochondrial dysfunctions and inflammation in mouse model of Parkinson's disease. literature abstract metadata
- T2 Garcinol enriched fraction of Garcinia morella (Gaertn.) Desr. fruit rind improves gut health and reduces the risk of nonalcoholic fatty liver disease by regulating PCK1/ACC/SREBP1/FASn pathway in a mouse model. literature abstract metadata