Solomon's Seal
Polygonatum
Polygonatum, a traditional plant with roots in various Asian medicinal practices, is primarily known for its potential health benefits. While specific traditional uses are not well-documented, it has been explored in modern scientific research for its biological activities. Studies have shown that Polygonatum polysaccharide microspheres encapsulating Clostridium butyricum may enhance probiotic efficacy and improve oral delivery, potentially benefiting individuals with inflammatory bowel disease. Additionally, mechanochemical resonance mixing has enabled the creation of stable dispersions from Polygonatum, enhancing renal imaging performance. Foliar-applied honokiol in Polygonatum cyrtonema Hua can be transported to the roots, offering a strategy for managing root rot disease. In terms of safety and drug interactions, no major issues or recorded interactions have been identified, though further research is needed to fully understand its potential effects.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Polygonatum polysaccharides improved psoriasis symptoms in mice and reduced keratinocyte proliferation and inflammation via JAK2/STAT3 pathway modulation.
- The study found that mechanochemical resonance mixing enabled the creation of stable Cy7-PAMAM dispersions, enhancing solubility, stability, and renal imaging performance.
- Polygonatum polysaccharide microspheres encapsulating Clostridium butyricum showed improved performance in oral delivery and enhanced probiotic efficacy for modulating the inflammatory bowel disease microenvironment.
- Foliar-applied honokiol can be transported downward to the roots in Polygonatum cyrtonema Hua, offering a strategy for managing root rot disease.
- The study identified 11 WOX genes in Polygonatum cyrtonema, suggesting potential roles in regeneration but without specific health claims.
- PCP1 improved insulin resistance and glycolipid metabolic disorders in T2DM mice by ameliorating gut microbiota imbalance and glucose metabolism disorder.
- The study identified Penicillium crustosum as the causal agent of root rot in Polygonatum kingianum.
- The study found that various drying methods had different impacts on Polygonatum cyrtonema Hua's quality attributes, with vacuum drying offering a good balance between energy consumption and product quality.
Frequently asked questions
What is Solomon's Seal?
Solomon's Seal (Polygonatum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Solomon's Seal?
8 sourced findings are recorded for Solomon's Seal; the strongest carries evidence grade D. For example: Polygonatum polysaccharides improved psoriasis symptoms in mice and reduced keratinocyte proliferation and inflammation via JAK2/STAT3 pathway modulation.
How strong is the evidence for Solomon's Seal?
The strongest finding for Solomon's Seal carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Solomon's Seal safe? What are the side effects?
No major safety issues are recorded for Solomon's Seal in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Solomon's Seal interact with medications?
No drug interactions are recorded for Solomon's Seal in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Solomon's Seal?
Solomon's Seal is also known as: Купена, Sceau-de-Salomon.
Is Solomon's Seal a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Foliar-applied honokiol exhibits basipetal translocation, offering a strategy for root disease management in precision agriculture systems. literature abstract metadata
- T2 Polygonatum polysaccharide microspheres encapsulated living Clostridium butyricum for mucosal barrier repair and immune regulation. literature abstract metadata
- T2 Resonance Acoustic Mixing-Enabled Non-covalent Loading of Cy7 for Enhanced Solubility, Stability, and Fluorescent Imaging Performance. literature abstract metadata
- T2 Ameliorative effect of Polygonatum cyrtonema Hua polysaccharide on HFD/STZ-induced type 2 diabetes mice via improving gut microbiota imbalance and glucose metabolism disorder. literature abstract metadata
- T2 Polygonatum polysaccharides inhibit keratinocyte proliferation and inflammation via JAK2/STAT3 pathway modulation in psoriasis. literature abstract metadata
- T2 Evaluation of Various Drying Methods for Polygonatum cyrtonema Hua: Effects on Drying Characteristics and Multidimensional Quality Assessment. literature abstract metadata
- T2 First Report and Biological Characterization of Penicillium crustosum Causing Root Rot in Polygonatum kingianum (Yunnan, China). literature abstract metadata
- T2 Genome-Wide Characterization of the WOX Gene Family in Polygonatum cyrtonema and Its Applications for Regeneration. literature abstract metadata