FolkKB

Claries

Salvia

Salvia is a genus of plants with diverse species, including Salvia miltiorrhiza and Salvia officinalis. Traditionally, there are no specific records indicating traditional uses for these plants across various cultures. Scientifically, studies have shown that SmGA2ox4 enhances salt tolerance and tanshinone accumulation in S. miltiorrhiza, while extracts from S. officinalis derived polymer-stabilized CuO-ZnO hybrid nanocomplexes exhibit antimicrobial activity and controlled protein delivery. Additionally, Salvia multicaulis contains bioactive compounds with potential anti-inflammatory and chemopreventive properties, though the effects can vary among species. Tanshinones from S. miltiorrhiza demonstrate multi-target neuroprotective effects in cerebral ischemia/reperfusion injury through various mechanisms. Safety concerns are minimal, with no major issues recorded. There are also no reported drug interactions associated with these plants.

At a glance
Best evidence
A
Cautions
—

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • The study found that SmGA2ox4 enhances salt tolerance and tanshinone accumulation in Salvia miltiorrhiza. D PMID
  • The study found that polymer-stabilized CuO-ZnO hybrid nanocomplexes derived from Salvia officinalis extracts exhibited antimicrobial activity and controlled protein delivery. D PMID
  • The study found that Salvia multicaulis contains bioactive compounds with potential anti-inflammatory and chemopreventive properties, though effects vary among species. D PMID
  • Tanshinones from Salvia miltiorrhiza show multi-target neuroprotective effects in cerebral ischemia/reperfusion injury through various mechanisms. D PMID
  • The study finds that ATF3, regulated by compounds like Salvia miltiorrhiza derivatives, shows promise in managing obesity-related metabolic and vascular disorders. D PMID
  • The study evaluated six Salvia species native to Türkiye and found S. dorystaechas to have potent antioxidant activity, while safety profiles suggested limited systemic use. D PMID
  • The study documented 91 plant taxa used for respiratory conditions in Transylvania, with some uses supported by contemporary pharmacology. D PMID
  • Salvia tomentosa leaf extract-capped silver nanoparticles showed moderate DNA binding, enhanced antibacterial activity, and retained some antioxidant capacity. D PMID
  • The study found that formononetin and salvianolic acid B suppress pancreatic cancer progression by downregulating MBOAT2 and inhibiting the JAK/STAT signaling pathway. D PMID
  • Salvia miltiorrhiza extract showed high efficacy in enhancing left ventricular ejection fraction in heart failure patients. A PMID
  • Salvia miltiorrhiza-derived interventions significantly improved bone density, structure, and metabolism markers in animal models of osteoporosis. A PMID
  • Three novel Xenodidymella species were identified from Salvia sclarea roots, expanding the known host range. D PMID

Frequently asked questions

What is Claries?

Claries (Salvia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Claries?

12 sourced findings are recorded for Claries; the strongest carries evidence grade A. For example: The study found that SmGA2ox4 enhances salt tolerance and tanshinone accumulation in Salvia miltiorrhiza.

How strong is the evidence for Claries?

The strongest finding for Claries carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).

Is Claries safe? What are the side effects?

No major safety issues are recorded for Claries in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Claries interact with medications?

No drug interactions are recorded for Claries in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Claries?

Claries is also known as: шалфей.

Is Claries a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 Neurochemical Mechanisms Underlying Tanshinone-Mediated Neuroprotection and Formulation Strategies in Cerebral Ischemia/Reperfusion Injury. literature abstract metadata
  2. T2 Comprehensive metabolomic profiling of Egyptian Salvia species reveals promising leads for chemopreventive and anti-inflammatory drug development: In vitro and In silico study. literature abstract metadata
  3. T2 Polymer-stabilized amorphous CuO-ZnO hybrid nanocomplex as a promising candidate for antimicrobial therapy and controlled drug delivery with molecular docking insights. literature abstract metadata
  4. T2 SmGA2ox4 plays a positive role in improving the salt tolerance and tanshinone accumulation of Salvia miltiorrhiza. literature abstract metadata
  5. T2 Targeting pancreatic cancer progression: The formononetin and salvianolic acid B combination suppresses JAK/STAT signaling via MBOAT2 downregulation. literature abstract metadata
  6. T2 Pharmacological effects of Salvia miltiorrhiza-derived interventions on osteoporosis in animal models: a systematic review and meta-analysis. literature abstract metadata
  7. T2 Plant-Mediated Synthesis of Silver Nanoparticles Using Salvia tomentosa: Characterization and Evaluation of Their Multifunctional Biological Activities, Including DNA Binding. literature abstract metadata
  8. T2 Ethnopharmacobotanical investigation of plants used for respiratory disorders in Transylvania, Romania. literature abstract metadata
  9. T2 Efficacy of plant extracts in heart failure patients: a systematic review and network meta-analysis. literature abstract metadata
  10. T2 Evaluation of the Therapeutic Potential and Safety Profile of Six Salvia Species Native to Türkiye. literature abstract metadata
  11. T2 Endophytic Xenodidymella from Iranian medicinal plants: description of three novel species and a new host record. literature abstract metadata
  12. T2 ATF3 in Metabolic Homeostasis and Vascular Disease: Integrating Bibliometric Evidence with Therapeutic Potential. literature abstract metadata

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