Stephania erecta
Stephania erecta
Stephania erecta, a plant traditionally used in Chinese medicine, has not been documented for specific traditional uses. Scientific studies have isolated various alkaloids from Stephania erecta that exhibit nonselective cytotoxicity and antimalarial activity against Plasmodium falciparum; however, these findings are currently not considered promising as clinical candidates. Additionally, hemanthamine was identified with mild antihypertensive effects and cytotoxic properties, while new aporphine and isoquinoline alkaloids from Stephania pierrei tubers showed some antiplasmodial activity but also demonstrated varying degrees of cytotoxicity. No major safety concerns or drug interactions have been recorded for this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study isolated and characterized several alkaloids from Stephania erecta that showed nonselective cytotoxicity and antimalarial activity against Plasmodium falciparum, but are not currently promising as clinical candidates.
- The study identified hemanthamine from Stephania erecta with mild antihypertensive activity and cytotoxic effects against cells.
- The study isolated new aporphine and isoquinoline alkaloids from Stephania pierrei tubers, identifying some with cytotoxic and antimalarial activity.
- Stephania erecta isolates showed some antiplasmodial activity but also exhibited varying degrees of cytotoxicity.
Frequently asked questions
What is Stephania erecta?
Stephania erecta (Stephania erecta) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Stephania erecta?
4 sourced findings are recorded for Stephania erecta; the strongest carries evidence grade D. For example: The study isolated and characterized several alkaloids from Stephania erecta that showed nonselective cytotoxicity and antimalarial activity against Plasmodium falciparum, but are not currently promising as clinical candidates.
How strong is the evidence for Stephania erecta?
The strongest finding for Stephania erecta carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Stephania erecta safe? What are the side effects?
No major safety issues are recorded for Stephania erecta in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Stephania erecta interact with medications?
No drug interactions are recorded for Stephania erecta in our sources. This does not rule them out — check with a pharmacist.
Is Stephania erecta a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Volume 3 Isolated Compounds (H-M) literature abstract metadata
- T2 Cytotoxic and antimalarial alkaloids from the tubers of Stephania pierrei. literature abstract metadata
- T2 Cytotoxic and antimalarial bisbenzylisoquinoline alkaloids from Stephania erecta. literature abstract metadata
- T2 Antiplasmodial and cytotoxic activity of natural bisbenzylisoquinoline alkaloids. literature abstract metadata