Quinquina
Cinchona · Cinchona Bark
Cinchona is a genus of trees native to South America. Its traditional use for treating malaria dates back centuries, particularly in indigenous Andean cultures. The bark contains quinine and other alkaloids that have been historically used against fevers and malaria. Scientific evidence supports the use of cinchona alkaloids in the treatment of malaria, although studies are limited and results vary. Research indicates potential applications in asymmetric organic synthesis, such as enantioselective addition reactions and cycloadditions, though these findings do not directly relate to traditional medicinal uses. No significant safety concerns or drug interactions have been reported for cinchona use in traditional medicine.
- Meilleure preuve
- D
- Précautions
- —
Information uniquement. L'usage traditionnel ne signifie pas une efficacité prouvée. Les preuves et la sécurité varient — consultez les sources citées.
Ce que dit la science
- This study reports a silver-catalyzed asymmetric [3+2] cycloaddition reaction that constructs C-N axial chirality and two stereocenters in oxazolines with high yields and selectivities.
- Le travail de Torti a mis en évidence l'utilisation thérapeutique de la bûche de quinquina pour le traitement de la malaria, contribuant à sa diffusion en Europe.
- Cette étude rapporte une addition enantioselective réussie de thiols à des ketimines de pirazolone utilisant des catalyseurs organiques dérivés d'alkaïdes de cinchona, atteignant des rendements élevés et une sélectivité enantio.
- Des catalyseurs péptidiques et de cinchona ont été identifiés qui surclassent la réactivité de fond pour l'acétylation trifluoromethyl asymétrique des sulfondiamines.
Frequently asked questions
What is Quinquina?
Quinquina (Cinchona) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Quinquina?
4 sourced findings are recorded for Quinquina; the strongest carries evidence grade D. For example: This study reports a silver-catalyzed asymmetric [3+2] cycloaddition reaction that constructs C-N axial chirality and two stereocenters in oxazolines with high yields and selectivities.
How strong is the evidence for Quinquina?
The strongest finding for Quinquina carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Quinquina safe? What are the side effects?
No major safety issues are recorded for Quinquina in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Quinquina interact with medications?
No drug interactions are recorded for Quinquina in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Quinquina?
Quinquina is also known as: Cinchona Bark, Хинное дерево.
Is Quinquina a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Assessment of Complementary Catalysts in an Uncharted Enantioselective Reaction of Sulfondiimines. literature abstract metadata
- T2 Enantioselective Addition of Thiols to Pyrazolone Ketimines by Cinchona Alkaloid-Derived C-2' Amino Organocatalyst. literature abstract metadata
- T2 Silver-catalyzed asymmetric [3+2] cycloaddition via dynamic kinetic resolution: access to chiral oxazolines bearing C-N axial chirality. literature abstract metadata
- T2 Francesco Torti (1658-1741) and his description on the therapeutic use of quinine: the first effective method of treating malaria based on an extract of the bark of the Peruvian cinchona tree. literature abstract metadata