Cinchona Bark
Cinchona
金鸡纳是一种原产于南美洲安第斯山脉地区的树木。传统上，其树皮被用于治疗疟疾，如Torti的工作所指出的那样，在欧洲强调了其治疗用途。科学证据支持奎宁类生物碱对疟原虫的有效性，但这些证据有限，并主要基于历史使用情况而非广泛的现代临床试验。没有记录到重大安全问题或药物相互作用，表明在适当管理下，可以安全地使用金鸡纳。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 这项研究报道了一种银催化的不对称[3+2]环加成反应，该反应在高产率和选择性下构建了C-N轴手性和两个立体中心的噁唑啉。
- 托蒂的工作强调了金鸡纳树皮在治疗疟疾方面的疗效，并促进了其在欧洲的传播。
- 这项研究报道了使用从奎宁碱衍生的C-2'氨基有机催化剂对吡唑酮酮亚胺进行选择性加硫的成功案例，实现了高产率和对映体选择性。
- 发现了既能肽类又能奎宁催化的不对称三氟甲基化硫双胺反应。
Frequently asked questions
What is Cinchona Bark?
Cinchona Bark (Cinchona) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Cinchona Bark?
4 sourced findings are recorded for Cinchona Bark; the strongest carries evidence grade D. For example: 这项研究报道了一种银催化的不对称[3+2]环加成反应，该反应在高产率和选择性下构建了C-N轴手性和两个立体中心的噁唑啉。
How strong is the evidence for Cinchona Bark?
The strongest finding for Cinchona Bark carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Cinchona Bark safe? What are the side effects?
No major safety issues are recorded for Cinchona Bark in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Cinchona Bark interact with medications?
No drug interactions are recorded for Cinchona Bark in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Cinchona Bark?
Cinchona Bark is also known as: Хинное дерево, Quinquina.
Is Cinchona Bark a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Assessment of Complementary Catalysts in an Uncharted Enantioselective Reaction of Sulfondiimines. literature abstract metadata
- T2 Enantioselective Addition of Thiols to Pyrazolone Ketimines by Cinchona Alkaloid-Derived C-2' Amino Organocatalyst. literature abstract metadata
- T2 Silver-catalyzed asymmetric [3+2] cycloaddition via dynamic kinetic resolution: access to chiral oxazolines bearing C-N axial chirality. literature abstract metadata
- T2 Francesco Torti (1658-1741) and his description on the therapeutic use of quinine: the first effective method of treating malaria based on an extract of the bark of the Peruvian cinchona tree. literature abstract metadata