Fan-leaf mountain yam
Dioscorea nipponica
Dioscorea nipponica is a plant traditionally not associated with any specific medicinal uses. Scientific evidence suggests that mild drought conditions can significantly enhance diosgenin content in its rhizomes, increasing it by 103.19 ± 2.63% compared to control conditions. The plant has shown potential anti-proliferative effects both in vitro and in vivo, with studies indicating a reduction in tumor volume ranging from 26-50%. Additionally, Dioscorea nipponica has been found to reduce pro-inflammatory cytokines and inhibit enzymes involved in neuroinflammation. A haplotype-resolved genome of the plant has also been sequenced, providing insights into dioscin biosynthesis and revealing four principal clades with varying ploidy levels. No major safety issues or drug interactions have been recorded for this plant.
- Meilleure preuve
- A
- Précautions
- —
Information uniquement. L'usage traditionnel ne signifie pas une efficacité prouvée. Les preuves et la sécurité varient — consultez les sources citées.
Ce que dit la science
- Une légère sécheresse a considérablement augmenté le contenu de diosgenine dans les rhizomes de Dioscorea nipponica de 103,19 ± 2,63% par rapport aux conditions de contrôle.
- Les deux PGP et DN ont inhibé de manière significative la synthèse du DNA et le réingrédient du cycle cellulaire (transition G0 à G1) in vitro, et ont réduit la taille des tumeurs de 26-50% in vivo.
- L'étude présente un génome résolu en haplotype de Dioscorea nipponica, identifiant des gènes clés dans la biosynthèse de dioscin et révélant quatre principaux cladès avec différents niveaux de ploïdie.
- L'étude a montré que Dioscorea nipponica réduit les cytokines pro-inflammatoires et inhibe des enzymes impliquées dans l'infiammation neurologique.
- La Dioscorea nipponica montre des effets multi-cibles en modulant les voies inflammatoires et apoptotiques dans les maladies auto-immunes, mais de grandes études sont nécessaires pour confirmer son potentiel thérapeutique.
- Des différences significatives ont été observées dans les métabolites secondaires entre les populations cultivées et sauvages de Dioscorea nipponica, malgré une stabilité génétique et une plus grande diversité.
- La sous-famille UGT73 chez D. nipponica montre diverses fonctions catégorielles dans la glycosylation des saponines stéroïdiennes, avec certaines fonctions évoluant de manière indépendante chez différentes familles.
Frequently asked questions
What is Fan-leaf mountain yam?
Fan-leaf mountain yam (Dioscorea nipponica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Fan-leaf mountain yam?
7 sourced findings are recorded for Fan-leaf mountain yam; the strongest carries evidence grade A. For example: Une légère sécheresse a considérablement augmenté le contenu de diosgenine dans les rhizomes de Dioscorea nipponica de 103,19 ± 2,63% par rapport aux conditions de contrôle.
How strong is the evidence for Fan-leaf mountain yam?
The strongest finding for Fan-leaf mountain yam carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Fan-leaf mountain yam safe? What are the side effects?
No major safety issues are recorded for Fan-leaf mountain yam in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Fan-leaf mountain yam interact with medications?
No drug interactions are recorded for Fan-leaf mountain yam in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Fan-leaf mountain yam?
Fan-leaf mountain yam is also known as: Диоскорея ниппонская.
Is Fan-leaf mountain yam a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Molecular Mechanisms Underlying Neuroinflammation Intervention with Medicinal Plants: A Critical and Narrative Review of the Current Literature. literature abstract metadata
- T2 Haplotype-resolved genome and population genomics provide insights into dioscin biosynthesis and evolutionary history of the medicinal species Dioscorea nipponica. literature abstract metadata
- T2 Inhibition of Dormant Lung Cancer Cell Reactivation by Punica Granatum Peel and Dioscorea Nipponica: Involving MYC, SKP2 and p27. literature abstract metadata
- T2 Dioscorea nipponica Makino: Unraveling multi-target mechanisms and clinical potential in autoimmune disease therapy. literature abstract metadata
- T2 Mild Drought Promotes Biomass Accumulation and Increases Diosgenin Content in Rhizomes of Dioscorea nipponica. literature abstract metadata
- T2 Habitat changes due to cultivation alter the genetic diversity and secondary metabolic changes of medicinal plants. literature abstract metadata
- T2 Chromosome-scale genome of Dioscorea nipponica and functional diversification of the DnUGT73 subfamily in steroidal saponin glycosylation. literature abstract metadata