Fan-leaf mountain yam
Dioscorea nipponica
Dioscorea nipponica is a plant traditionally not associated with any specific medicinal uses. Scientific evidence suggests that mild drought conditions can significantly enhance diosgenin content in its rhizomes, increasing it by 103.19 ± 2.63% compared to control conditions. The plant has shown potential anti-proliferative effects both in vitro and in vivo, with studies indicating a reduction in tumor volume ranging from 26-50%. Additionally, Dioscorea nipponica has been found to reduce pro-inflammatory cytokines and inhibit enzymes involved in neuroinflammation. A haplotype-resolved genome of the plant has also been sequenced, providing insights into dioscin biosynthesis and revealing four principal clades with varying ploidy levels. No major safety issues or drug interactions have been recorded for this plant.
- 最佳证据
- A
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 轻度干旱显著增加了 Dioscorea nipponica 根状茎中迪奥辛含量，比对照条件高 103.19 ± 2.63%。
- PGP 和 DN 均显著抑制了 DNA 合成和细胞周期重新进入（G0 到 G1 转换），体外实验中，体内实验肿瘤体积减少 26-50%。
- 该研究呈现了 Dioscorea nipponica 的单体型解析基因组，鉴定出二萜甜菜苷 biosynthesis 中的关键基因，并揭示了四个主要的倍性群集，具有不同的倍性水平。
- 研究发现，淫羊藿可以减少促炎细胞因子并抑制参与神经炎症的酶。
- Dioscorea nipponica 展现了通过调节炎症和凋亡途径在自身免疫性疾病中的多靶点效应，但需要大规模试验来确认其治疗潜力。
- 尽管 Dioscorea nipponica 的栽培种群和野生种群具有遗传稳定性和更高的多样性，但观察到次生代谢物存在显著差异。
- D. 小叶女贞中的UGT73亚家族在甾体皂苷糖基化中表现出多种催化功能，其中一些功能独立地由不同的家族演化而来。
Frequently asked questions
What is Fan-leaf mountain yam?
Fan-leaf mountain yam (Dioscorea nipponica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Fan-leaf mountain yam?
7 sourced findings are recorded for Fan-leaf mountain yam; the strongest carries evidence grade A. For example: 轻度干旱显著增加了 Dioscorea nipponica 根状茎中迪奥辛含量，比对照条件高 103.19 ± 2.63%。
How strong is the evidence for Fan-leaf mountain yam?
The strongest finding for Fan-leaf mountain yam carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Fan-leaf mountain yam safe? What are the side effects?
No major safety issues are recorded for Fan-leaf mountain yam in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Fan-leaf mountain yam interact with medications?
No drug interactions are recorded for Fan-leaf mountain yam in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Fan-leaf mountain yam?
Fan-leaf mountain yam is also known as: Диоскорея ниппонская.
Is Fan-leaf mountain yam a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Molecular Mechanisms Underlying Neuroinflammation Intervention with Medicinal Plants: A Critical and Narrative Review of the Current Literature. literature abstract metadata
- T2 Haplotype-resolved genome and population genomics provide insights into dioscin biosynthesis and evolutionary history of the medicinal species Dioscorea nipponica. literature abstract metadata
- T2 Inhibition of Dormant Lung Cancer Cell Reactivation by Punica Granatum Peel and Dioscorea Nipponica: Involving MYC, SKP2 and p27. literature abstract metadata
- T2 Dioscorea nipponica Makino: Unraveling multi-target mechanisms and clinical potential in autoimmune disease therapy. literature abstract metadata
- T2 Mild Drought Promotes Biomass Accumulation and Increases Diosgenin Content in Rhizomes of Dioscorea nipponica. literature abstract metadata
- T2 Habitat changes due to cultivation alter the genetic diversity and secondary metabolic changes of medicinal plants. literature abstract metadata
- T2 Chromosome-scale genome of Dioscorea nipponica and functional diversification of the DnUGT73 subfamily in steroidal saponin glycosylation. literature abstract metadata