Astral Sage
Salvia miltiorrhiza
Salvia miltiorrhiza, commonly known as Danshen, is a traditional Chinese herb. Traditionally, it has been used in Chinese medicine for various conditions such as cardiovascular disorders and menstrual issues, though specific uses are not extensively recorded. Scientific evidence suggests that overexpression of SmGA2ox4 enhances the salt tolerance and tanshinone accumulation in S. miltiorrhiza, indicating potential benefits related to environmental stress resistance. Tanshinones from this plant have shown multi-target neuroprotective effects in cerebral ischemia/reperfusion injury through various mechanisms, though evidence is still being explored. Additionally, studies indicate that SAB can synergistically enhance the activity of azoles against drug-resistant C. glabrata both in vitro and in vivo, while PB-SM administration improved immune function in cyclophosphamide-induced immunosuppressed mice, with individual and enhanced effects from PCA and TanIIA. Notably, no major safety issues or significant drug interactions have been recorded for S. miltiorrhiza to date.
- Meilleure preuve
- A
- Précautions
- —
Information uniquement. L'usage traditionnel ne signifie pas une efficacité prouvée. Les preuves et la sécurité varient — consultez les sources citées.
Ce que dit la science
- L'overexpression de SmGA2ox4 améliore la tolérance à l'eau de mer et l'accumulation de tanacétine chez Salvia miltiorrhiza.
- Les tanines de Salvia miltiorrhiza montrent des effets neuroprotecteurs multirécepteurs dans l’ischémie/reperfusion cérébrale par différents mécanismes.
- Le SAB amplifie synergiquement l'activité des azoles contre le C. glabrata résistant, tant in vitro qu'in vivo.
- L'administration de PB-SM a amélioré la fonction immunitaire chez les souris immunodéprimées par cyclophosphamide, avec des effets individuels et renforcés par PCA et TanIIA.
- Les interventions issues de Salvia miltiorrhiza ont considérablement amélioré la densité osseuse, la structure et les marqueurs métaboliques chez les modèles animaux d'ostéoporose.
- L'étude a montré que la formononetine et l'acide salvianol B réduisent la progression du cancer pancréatique en régulant le niveau de MBOAT2 et en inhibant le chemin de signalisation JAK/STAT.
- L'étude a montré que les Gouttes Qishen Yiqi atténuent l'innervation fibreuse due à l'ischémie-réperfusion chez le miocarde en ciblant la voie TGF-β/Periostin.
- La pâte Qishen a amélioré la传导性与心脏功能在心力衰竭小鼠中通过上调心肌驻留巨噬细胞中的Cx43得到了改善。
- The study finds that Atf3 deficiency significantly impacts perivascular adipose tissue structure and function, suggesting Atf3's importance in adipose-vascular crosstalk.
- L'extrait de Salvia miltiorrhiza a montré une grande efficacité pour améliorer l'fraction d'éjection du ventricule gauche chez les patients souffrant d'une insuffisance cardiaque.
- L'extrait de Salvia miltiorrhiza (SAGX) a montré une réduction significativement plus grande de l'IPSS totale par rapport au palissandre, avec des améliorations des symptômes d'entreposage et de la QoL.
Frequently asked questions
What is Astral Sage?
Astral Sage (Salvia miltiorrhiza) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Astral Sage?
11 sourced findings are recorded for Astral Sage; the strongest carries evidence grade A. For example: L'overexpression de SmGA2ox4 améliore la tolérance à l'eau de mer et l'accumulation de tanacétine chez Salvia miltiorrhiza.
How strong is the evidence for Astral Sage?
The strongest finding for Astral Sage carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Astral Sage safe? What are the side effects?
No major safety issues are recorded for Astral Sage in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Astral Sage interact with medications?
No drug interactions are recorded for Astral Sage in our sources. This does not rule them out — check with a pharmacist.
Is Astral Sage a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Protocatechuic acid and tanshinone IIA improve cyclophosphamide-induced immunosuppression. literature abstract metadata
- T2 Salvianolic acid B synergizes with azoles against Candida glabrata cells in vulvovaginal candidiasis. literature abstract metadata
- T2 Neurochemical Mechanisms Underlying Tanshinone-Mediated Neuroprotection and Formulation Strategies in Cerebral Ischemia/Reperfusion Injury. literature abstract metadata
- T2 SmGA2ox4 plays a positive role in improving the salt tolerance and tanshinone accumulation of Salvia miltiorrhiza. literature abstract metadata
- T2 Qishen Paste Improves Cardiac Conduction in Heart Failure by Regulating Cardiac Resident Macrophage Connexin43. literature abstract metadata
- T2 Qishen Yiqi Dripping Pills Alleviate Myocardial Ischemia-Reperfusion-Induced Fibrotic Injury by Inhibiting Fibroblast Activation via the Transforming Growth Factor-Beta/Periostin Pathway. literature abstract metadata
- T2 Targeting pancreatic cancer progression: The formononetin and salvianolic acid B combination suppresses JAK/STAT signaling via MBOAT2 downregulation. literature abstract metadata
- T2 Pharmacological effects of Salvia miltiorrhiza-derived interventions on osteoporosis in animal models: a systematic review and meta-analysis. literature abstract metadata
- T2 Efficacy of plant extracts in heart failure patients: a systematic review and network meta-analysis. literature abstract metadata
- T2 Efficacy and Safety of Salvia miltiorrhiza Extract (SAGX) Compared with Saw Palmetto in Men with Lower Urinary Tract Symptoms: A 12-Week, Randomized, Double-Blind, Parallel-Group Pilot Study. literature abstract metadata
- T2 ATF3 in Metabolic Homeostasis and Vascular Disease: Integrating Bibliometric Evidence with Therapeutic Potential. literature abstract metadata