Astral Sage
Salvia miltiorrhiza
Salvia miltiorrhiza（中药名为丹参）是一种传统上用于多种健康问题的植物，包括心血管疾病和炎症。虽然其具体用途在传统实践中并未得到广泛记录，但科学研究已显示出有前景的结果。研究表明，SmGA2ox4 的过表达可增强 S. miltiorrhiza 对盐胁迫的耐受性，并促进丹参酮积累，从而提示潜在的适应原效益。此外，该植物的丹参酮通过多种机制，在脑缺血/再灌注损伤中表现出多靶点神经保护作用。进一步研究表明，SAB 能与抗真菌药物协同增强对耐药性 C. glabrata 的 azole 活性，无论是在体外还是在体内，都显示其潜在的抗微生物特性。在另一项研究中，PB‑SM 给药改善了环磷酰胺诱导免疫抑制小鼠的免疫功能，并且 PCA 与 TanIIA 的单独及增强效应均得到验证。就安全性而言，目前未记录 S. miltiorrhiza 存在重大问题，也没有已报告的药物相互作用。
- 最佳证据
- A
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- SmGA2ox4 过表达增强了丹参中盐忍耐性和丹参酮积累。
- 丹参中的丹酚酸通过多种机制在脑缺血/再灌注损伤中表现出多靶点神经保护作用。
- SAB 协同增强唑类药物对耐药性 C. glabrata 的活性，无论是体外还是体内。
- PB-SM 的给药改善了环磷酰胺诱导的免疫抑制小鼠的免疫功能，单体和增强效果来自 PCA 和 TanIIA。
- 来源于 Salvia miltiorrhiza 的干预措施显著改善了动物模型中骨密度、结构和代谢标志物。
- 研究发现，黄酮苷元和 Salvianolic 酸 B 可通过下调 MBOAT2 和抑制 JAK/STAT 信号通路来抑制胰腺癌的进展。
- 研究发现，芪 Shen 生脉滴丸通过靶向TGF-β/骨连接蛋白途径减轻心肌缺血再灌注引起的纤维化损伤。
- Qishen膏通过上调心肌驻留巨噬细胞中的Cx43改善了心力衰竭小鼠的心脏传导和功能。
- 研究发现，Atf3 缺陷显著影响周围血管脂肪组织的结构和功能，表明 Atf3 在脂肪-血管对话中的重要性。
- 丹参提取物在心力衰竭患者中显示出提高左室射血分数的高疗效。
- Salvia miltiorrhiza 提取物（SAGX）在减少总IPSS方面显示出显著更大的降低，与锯棕榈相比，在储存症状和生活质量方面有所改善。
Frequently asked questions
What is Astral Sage?
Astral Sage (Salvia miltiorrhiza) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Astral Sage?
11 sourced findings are recorded for Astral Sage; the strongest carries evidence grade A. For example: SmGA2ox4 过表达增强了丹参中盐忍耐性和丹参酮积累。
How strong is the evidence for Astral Sage?
The strongest finding for Astral Sage carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Astral Sage safe? What are the side effects?
No major safety issues are recorded for Astral Sage in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Astral Sage interact with medications?
No drug interactions are recorded for Astral Sage in our sources. This does not rule them out — check with a pharmacist.
Is Astral Sage a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Protocatechuic acid and tanshinone IIA improve cyclophosphamide-induced immunosuppression. literature abstract metadata
- T2 Salvianolic acid B synergizes with azoles against Candida glabrata cells in vulvovaginal candidiasis. literature abstract metadata
- T2 Neurochemical Mechanisms Underlying Tanshinone-Mediated Neuroprotection and Formulation Strategies in Cerebral Ischemia/Reperfusion Injury. literature abstract metadata
- T2 SmGA2ox4 plays a positive role in improving the salt tolerance and tanshinone accumulation of Salvia miltiorrhiza. literature abstract metadata
- T2 Qishen Paste Improves Cardiac Conduction in Heart Failure by Regulating Cardiac Resident Macrophage Connexin43. literature abstract metadata
- T2 Qishen Yiqi Dripping Pills Alleviate Myocardial Ischemia-Reperfusion-Induced Fibrotic Injury by Inhibiting Fibroblast Activation via the Transforming Growth Factor-Beta/Periostin Pathway. literature abstract metadata
- T2 Targeting pancreatic cancer progression: The formononetin and salvianolic acid B combination suppresses JAK/STAT signaling via MBOAT2 downregulation. literature abstract metadata
- T2 Pharmacological effects of Salvia miltiorrhiza-derived interventions on osteoporosis in animal models: a systematic review and meta-analysis. literature abstract metadata
- T2 Efficacy of plant extracts in heart failure patients: a systematic review and network meta-analysis. literature abstract metadata
- T2 Efficacy and Safety of Salvia miltiorrhiza Extract (SAGX) Compared with Saw Palmetto in Men with Lower Urinary Tract Symptoms: A 12-Week, Randomized, Double-Blind, Parallel-Group Pilot Study. literature abstract metadata
- T2 ATF3 in Metabolic Homeostasis and Vascular Disease: Integrating Bibliometric Evidence with Therapeutic Potential. literature abstract metadata