bergamot orange

Citrus ×bergamia, commonly known as bergamot, is a citrus plant native to southern Italy and has been used in traditional medicine primarily for its aromatic properties. It is traditionally utilized in aromatherapy and culinary applications but lacks specific recorded uses in traditional medical practices. Scientific evidence suggests that bergamot supplementation may be beneficial for individuals with overweight or obesity, as it has shown significant decreases in body weight, body mass index, and waist circumference. Additionally, studies indicate that bergamot essential oil, when used in aromatherapy alongside lavender, can improve menopausal symptoms and sleep quality; however, combining it with mindfulness-based therapy did not provide additional benefits. A standardized phospholipid-formulated bergamot extract demonstrated dose-dependent activation of GLP-1R signaling without affecting DPP4 or GLUT4 pathways. Moreover, bergamot (PB) treatment was found to reduce triglyceride accumulation and modulate fatty acid composition in skeletal muscle, while improving oxidative stress and inflammatory markers in an experimental model of metabolic syndrome. Safety concerns are minimal; no major issues have been recorded. Similarly, there is currently no evidence suggesting significant drug interactions with bergamot.

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