Goa-butter

Garcinia indica

Garcinia indica, commonly known as kokum, is a traditional plant native to India. It has been used in Ayurvedic and traditional Indian medicine for various purposes, though specific uses are not well-documented. Scientific studies suggest potential benefits such as improved memory functions and neuroprotection through the inhibition of HAT enzymes, and mitigating Alzheimer's-like symptoms by regulating oxidative stress, acetylcholinesterase (AChE) activity, and pro-inflammatory cytokines in Drosophila melanogaster models. Additionally, a combined supplementation with astaxanthin showed promise in modulating redox status and lysosomal degradation in murine models of non-alcoholic fatty liver disease (NAFLD), though the effects were not always synergistic. Garcinol from Garcinia indica also exhibits potential as an epigenetic modulator with anti-cancer activities, but further human trials are needed for clinical application. No major safety issues or drug interactions have been recorded to date.

لمحة سريعة
أفضل دليل
D
تحذيرات

للمعلومات فقط. الاستخدام التقليدي لا يعني فعاليّة مثبتة. تختلف الأدلة والسلامة — راجع المصادر المذكورة.

ما يقوله العلم

  • تشير الدراسة إلى أن غارسينول من Garcinia indica قد يحسن الوظائف الذاكرةية والحماية العصبية بشكل محتمل عن طريق حجب إنزيمات HAT. D PMID
  • ظهر garciniol من Garcinia indica إمكانية في تخفيف التدهور العصبي المماثل لمرض ألزهايمر في Drosophila melanogaster عن طريق تنظيم應为“أكسидاتيف” - стресс الأكسدة، نشاط AChE وخلايا الالتهاب المحتملة. D PMID
  • الغاريسيول، المستخرج من غارسينيا إنديكا، يظهر إمكانات كمثبط إپي جيني مع نشاطات مضادة للسرطان، لكن الدراسات البشرية الإضافية مطلوبة. D PMID
  • تم تكييف التكميم المركب مع الأستاكسانتين والكوكوم لتكييف الحالة الرديكسية والتآكل اللزوسومي في نموذج الفئران للتهاب الكبد الدهني غير الكحولي الناجم عن النظام الغذائي. D PMID

Frequently asked questions

What is Goa-butter?

Goa-butter (Garcinia indica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Goa-butter?

4 sourced findings are recorded for Goa-butter; the strongest carries evidence grade D. For example: تشير الدراسة إلى أن غارسينول من Garcinia indica قد يحسن الوظائف الذاكرةية والحماية العصبية بشكل محتمل عن طريق حجب إنزيمات HAT.

How strong is the evidence for Goa-butter?

The strongest finding for Goa-butter carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Goa-butter safe? What are the side effects?

No major safety issues are recorded for Goa-butter in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Goa-butter interact with medications?

No drug interactions are recorded for Goa-butter in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Goa-butter?

Goa-butter is also known as: гарциния индийская.

Is Goa-butter a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

المصادر

  1. T2 Garcinol as an Epigenetic Modulator: Mechanisms of Anti-Cancer Activity and Therapeutic Potential. literature abstract metadata
  2. T2 Antioxidant Intervention in NAFLD: Astaxanthin and Kokum Modulate Redox Status and Lysosomal Degradation. literature abstract metadata
  3. T2 Protective effects of the natural polyphenol garcinol from Garcinia indica mitigates aluminium chloride-induced Alzheimer's-like neurodegeneration in Drosophila melanogaster. literature abstract metadata
  4. T2 Epigenetic Modulation Is a Key Mechanism in Cognitive Deficit: Unveiling Garcinol as a Potent HAT Inhibitor in Improving Alzheimer's Disease. literature abstract metadata