Goa-butter
Garcinia indica
Garcinia indica, commonly known as kokum, is a traditional plant native to India. It has been used in Ayurvedic and traditional Indian medicine for various purposes, though specific uses are not well-documented. Scientific studies suggest potential benefits such as improved memory functions and neuroprotection through the inhibition of HAT enzymes, and mitigating Alzheimer's-like symptoms by regulating oxidative stress, acetylcholinesterase (AChE) activity, and pro-inflammatory cytokines in Drosophila melanogaster models. Additionally, a combined supplementation with astaxanthin showed promise in modulating redox status and lysosomal degradation in murine models of non-alcoholic fatty liver disease (NAFLD), though the effects were not always synergistic. Garcinol from Garcinia indica also exhibits potential as an epigenetic modulator with anti-cancer activities, but further human trials are needed for clinical application. No major safety issues or drug interactions have been recorded to date.
- Meilleure preuve
- D
- Précautions
- —
Information uniquement. L'usage traditionnel ne signifie pas une efficacité prouvée. Les preuves et la sécurité varient — consultez les sources citées.
Ce que dit la science
- L'étude suggère que le Garcinol de Garcinia indica pourrait potentiellement améliorer les fonctions de mémoire et la neuroprotection en inhibant les enzymes HAT.
- Le garciniol de Garcinia indica a montré un potentiel pour atténuer la neurodégénérescence alzheimerienne chez Drosophila melanogaster en régulant le stress oxydatif, l'activité de l'AChE et les cytokines pro-inflammatoires.
- Le garciniol, dérivé de Garcinia indica, montre du potentiel comme modulateur épigénétique avec des activités anticancéreuses, mais des études humaines supplémentaires sont nécessaires.
- Une supplémentation combinée à l'astaxanthine et au kokum a modulé l'état rédox et la dégradation lysosomale dans un modèle murin d'NAFLD induite par une alimentation.
Frequently asked questions
What is Goa-butter?
Goa-butter (Garcinia indica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Goa-butter?
4 sourced findings are recorded for Goa-butter; the strongest carries evidence grade D. For example: L'étude suggère que le Garcinol de Garcinia indica pourrait potentiellement améliorer les fonctions de mémoire et la neuroprotection en inhibant les enzymes HAT.
How strong is the evidence for Goa-butter?
The strongest finding for Goa-butter carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Goa-butter safe? What are the side effects?
No major safety issues are recorded for Goa-butter in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Goa-butter interact with medications?
No drug interactions are recorded for Goa-butter in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Goa-butter?
Goa-butter is also known as: гарциния индийская.
Is Goa-butter a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Garcinol as an Epigenetic Modulator: Mechanisms of Anti-Cancer Activity and Therapeutic Potential. literature abstract metadata
- T2 Antioxidant Intervention in NAFLD: Astaxanthin and Kokum Modulate Redox Status and Lysosomal Degradation. literature abstract metadata
- T2 Protective effects of the natural polyphenol garcinol from Garcinia indica mitigates aluminium chloride-induced Alzheimer's-like neurodegeneration in Drosophila melanogaster. literature abstract metadata
- T2 Epigenetic Modulation Is a Key Mechanism in Cognitive Deficit: Unveiling Garcinol as a Potent HAT Inhibitor in Improving Alzheimer's Disease. literature abstract metadata