Goa-butter

Garcinia indica

Garcinia indica, commonly known as kokum, is a traditional plant native to India. It has been used in Ayurvedic and traditional Indian medicine for various purposes, though specific uses are not well-documented. Scientific studies suggest potential benefits such as improved memory functions and neuroprotection through the inhibition of HAT enzymes, and mitigating Alzheimer's-like symptoms by regulating oxidative stress, acetylcholinesterase (AChE) activity, and pro-inflammatory cytokines in Drosophila melanogaster models. Additionally, a combined supplementation with astaxanthin showed promise in modulating redox status and lysosomal degradation in murine models of non-alcoholic fatty liver disease (NAFLD), though the effects were not always synergistic. Garcinol from Garcinia indica also exhibits potential as an epigenetic modulator with anti-cancer activities, but further human trials are needed for clinical application. No major safety issues or drug interactions have been recorded to date.

एक नज़र में
सर्वोत्तम प्रमाण
D
सावधानियाँ

केवल जानकारी हेतु। पारंपरिक उपयोग का अर्थ सिद्ध प्रभावशीलता नहीं है। प्रमाण और सुरक्षा भिन्न होती है — उद्धृत स्रोत देखें।

विज्ञान क्या कहता है

  • अध्ययन ताकतवर, गैर्सिनिया इंडिकाई से ली गई गैर्सिनोल की उपयुक्तता प्रतीत होती है कि वह HAT अनुक्रमणिकाओं को रोध करके स्मृति कार्यक्रम और न्यूरोप्रोटेक्शन में संभवतः सुधार कर सकती है। D PMID
  • गार्चिनिया इंडिका से गार्चिनोल की दृष्टि से Drosophila melanogaster में एल्जिझर्स जैसी न्यूरोडेजनरेशन प्रक्रिया को घटाने के लिए अवश्यकता हुई, ऑक्सीजनेटिव स्ट्रेस, AChE गतिबलिति और प्र-इंफ्लैमेटरी काइटोकाइनों को नियंत्रित करके। D PMID
  • गार्चिनिया इंडिका से प्राप्त गार्चिनोल, एपीजीनेटिक मॉडुलेटर के रूप में और विषमकर्मी दवा की क्षमताओं के साथ शक्ति प्रदर्शित करता है, लेकिन इसके लिए आगामी मानव अध्ययनों की जरूरत है। D PMID
  • अस्टाक्सानथिन और कोकम की संयुक्त पूरण एक माउस मॉडल में डाइटा-इन्डियैड नाफएलड में रेडक्स स्टेट और लिसोज़ोमिक डेग्रेडेशन को प्रतिबद्ध करती है। D PMID

Frequently asked questions

What is Goa-butter?

Goa-butter (Garcinia indica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Goa-butter?

4 sourced findings are recorded for Goa-butter; the strongest carries evidence grade D. For example: अध्ययन ताकतवर, गैर्सिनिया इंडिकाई से ली गई गैर्सिनोल की उपयुक्तता प्रतीत होती है कि वह HAT अनुक्रमणिकाओं को रोध करके स्मृति कार्यक्रम और न्यूरोप्रोटेक्शन में संभवतः सुधार कर सकती है।

How strong is the evidence for Goa-butter?

The strongest finding for Goa-butter carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Goa-butter safe? What are the side effects?

No major safety issues are recorded for Goa-butter in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Goa-butter interact with medications?

No drug interactions are recorded for Goa-butter in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Goa-butter?

Goa-butter is also known as: гарциния индийская.

Is Goa-butter a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

स्रोत

  1. T2 Garcinol as an Epigenetic Modulator: Mechanisms of Anti-Cancer Activity and Therapeutic Potential. literature abstract metadata
  2. T2 Antioxidant Intervention in NAFLD: Astaxanthin and Kokum Modulate Redox Status and Lysosomal Degradation. literature abstract metadata
  3. T2 Protective effects of the natural polyphenol garcinol from Garcinia indica mitigates aluminium chloride-induced Alzheimer's-like neurodegeneration in Drosophila melanogaster. literature abstract metadata
  4. T2 Epigenetic Modulation Is a Key Mechanism in Cognitive Deficit: Unveiling Garcinol as a Potent HAT Inhibitor in Improving Alzheimer's Disease. literature abstract metadata