Goa-butter
Garcinia indica
Garcinia indica, commonly known as kokum, is a traditional plant native to India. It has been used in Ayurvedic and traditional Indian medicine for various purposes, though specific uses are not well-documented. Scientific studies suggest potential benefits such as improved memory functions and neuroprotection through the inhibition of HAT enzymes, and mitigating Alzheimer's-like symptoms by regulating oxidative stress, acetylcholinesterase (AChE) activity, and pro-inflammatory cytokines in Drosophila melanogaster models. Additionally, a combined supplementation with astaxanthin showed promise in modulating redox status and lysosomal degradation in murine models of non-alcoholic fatty liver disease (NAFLD), though the effects were not always synergistic. Garcinol from Garcinia indica also exhibits potential as an epigenetic modulator with anti-cancer activities, but further human trials are needed for clinical application. No major safety issues or drug interactions have been recorded to date.
- Beste Evidenz
- D
- Warnhinweise
- —
Nur zur Information. Traditionelle Anwendung bedeutet keine nachgewiesene Wirksamkeit. Evidenz und Sicherheit variieren — siehe die angegebenen Quellen.
Was die Wissenschaft sagt
- Die Studie deutet darauf hin, dass Garcinol aus Garcinia indica möglicherweise die Gedächtnsfunktionen und die Neuroschutzreaktion durch die Inhibition von HAT-Enzymen verbessern könnte.
- Garcinol aus Garcinia indica zeigte Potenzial bei der Minderung von Alzheimerähnlicher Neurodegeneration in Drosophila melanogaster durch die Regulierung des氧化剂应为“oxidativen” - Stress, AChE-Aktivität und pro-inflammatorischer Cytokine.
- Garcinol, entnommen aus Garcinia indica, zeigt Potenzial als epigenetischer Modulator mit antitumoralen Aktivitäten, aber zusätzliche menschliche Studien sind notwendig.
- Eine kombinierte Supplementation mit Astaxanthin und Kokum modulierte den Redox-Zustand und die lysosomale Degradation in einem Mäusemodell für NAFLD durch Ernährung.
Frequently asked questions
What is Goa-butter?
Goa-butter (Garcinia indica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Goa-butter?
4 sourced findings are recorded for Goa-butter; the strongest carries evidence grade D. For example: Die Studie deutet darauf hin, dass Garcinol aus Garcinia indica möglicherweise die Gedächtnsfunktionen und die Neuroschutzreaktion durch die Inhibition von HAT-Enzymen verbessern könnte.
How strong is the evidence for Goa-butter?
The strongest finding for Goa-butter carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Goa-butter safe? What are the side effects?
No major safety issues are recorded for Goa-butter in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Goa-butter interact with medications?
No drug interactions are recorded for Goa-butter in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Goa-butter?
Goa-butter is also known as: гарциния индийская.
Is Goa-butter a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Quellen
- T2 Garcinol as an Epigenetic Modulator: Mechanisms of Anti-Cancer Activity and Therapeutic Potential. literature abstract metadata
- T2 Antioxidant Intervention in NAFLD: Astaxanthin and Kokum Modulate Redox Status and Lysosomal Degradation. literature abstract metadata
- T2 Protective effects of the natural polyphenol garcinol from Garcinia indica mitigates aluminium chloride-induced Alzheimer's-like neurodegeneration in Drosophila melanogaster. literature abstract metadata
- T2 Epigenetic Modulation Is a Key Mechanism in Cognitive Deficit: Unveiling Garcinol as a Potent HAT Inhibitor in Improving Alzheimer's Disease. literature abstract metadata